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Mianserin (hydrochloride)

(CAS: 21535-47-7)

Suppliers of Mianserin (hydrochloride)

Company Name Email Tel Country
AA Blocks LLC [email protected] +1 858-523-8231

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AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD72/100mg () USD120/200mg ()

Chongqing Succeway Pharmaceutical Co., Ltd. [email protected] +86 (23) 6862-4447 China

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Euticals S.p.A. [email protected] +39-0371-49-021/ +39 02 822 83 51 ITALY

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Jiaojiang Xinyou Chemical Factory [email protected] +86 (576) 8851-7139 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD72/100mg () USD120/200mg ()
Quality Control & MSDS Files: HNMR LCMS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HPLC HNMR HPLC HNMR HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD72/100mg () USD120/200mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .97 Brand: TargetMol

Price and Availability: USD65/5mg () USD127/10mg () USD203/25mg () USD330/50mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

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Background Information of Mianserin (hydrochloride)

Mianserin hydrochloride is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant. Target: H1 receptor Mianserin is a psychoactive drug of the tetracyclic antidepressant (TeCA) therapeutic family.

Solubility of Mianserin (hydrochloride)

Solubility Sources
DMSO 60 mg/mL (199 mM); Water 30 mg/mL (99 mM) MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 60 mg/mL (199.44 mM); Water30 mg/mL (99.72 mM); Ethanol21 mg/mL (69.8 mM) Selleck Chemicals LLC
Soluble to 10 mM in water Tocris Bioscience Inc.

Storage Condition of Mianserin (hydrochloride)

Storage Condition Sources
Store at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HPLC] [HNMR] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Immunology/Inflammation GPCR/G Protein
Target Histamine Receptor
Research Area Neurological Disease

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Mianserin (hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
300.83 C18H21ClN2 21535-47-7 Bolvidon; 1,2,3,4,10,14b-Hexahydro-2-methyl-dibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride; 2-methyl-1,2,3,4,10,14b-hexahydrodibenzo[c,f]pyrazino[1,2-a]azepine hydrochloride

Structure Information of Mianserin (hydrochloride)

Smiles CN1CC2N(CC1)C(C=CC=C3)=C3CC4=CC=CC=C24.Cl
InChI InChI=1S/C18H20N2.ClH/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19;/h2-9,18H,10-13H2,1H3;1H

Related Products

Other Form Products of Mianserin (hydrochloride)

Name CAS Formula Suppliers
Mianserin 24219-97-4 C18H20N2 7

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Safety Data of Mianserin (hydrochloride)

Hazard Symbols:Xi Risk Statements:R22 Safety Statements:7-16-36/37-45
Transport Information: HS Code: RTECS:HP8780000
WGK Germany:3

Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:>230oC (dec.)
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,60 mg/mL(199.44 mM);In vitro:Water,30 mg/mL(99.72 mM);In vitro:Ethanol,21 mg/mL(69.8 mM);
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:244-426-7
Optical Rotation: alpha:

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