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Piroxicam

(CAS: 36322-90-4)

Suppliers of Piroxicam

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AA Blocks LLC [email protected] +1 858-523-8231

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AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Alfa Chemistry [email protected] 1-201-478-8534 USA

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Arshine Technology Co., Ltd. [email protected] +86 (755) 3333-0822 China

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Freedom Chemical Supply [email protected] +1 (855) 615-3800 USA

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Hubie Xinyuanshun Pharm&Chem Co., Ltd. [email protected] +86 (27) 5066-4929 / +86 13971561712 China

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Kaifeng Pharmaceutical (Group) Co., Ltd. [email protected] +86 18737121931 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD60/1g () USD130/5g ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HPLC HPLC HPLC

Shandong Fangming Pharmaceutical Group Co., Ltd. [email protected],[email protected] +86 (530) 720-8439 / 519-8388 China

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD20/2mg () USD42/10mg () USD98/50mg () USD122/200mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Zhangjiagang For Chemical Co., Ltd. [email protected] +86 (512) 5679-6585 / 5897-6331 China

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Zhejiang Haisen Pharmaceutical Co., Ltd [email protected] +86-579-86773108 CHINA

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Background Information of Piroxicam

Piroxicam (Feldene) is a non-selective COX inhibitor with an IC50 of 6 mM. Target: COX Piroxicam, is non-steroidal anti-inflammatory and analgesic agent, which is widely used in the treatment of patients with rheumatologic disorders.

Solubility of Piroxicam

Solubility Sources
DMSO 66 mg/mL; Water <1 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 66 mg/mL (199.18 mM); Ethanol1 mg/mL (3.01 mM); Water<1 mg/mL (<1 mM) Selleck Chemicals LLC
Soluble to 100 mM in DMSO Tocris Bioscience Inc.

Storage Condition of Piroxicam

Storage Condition Sources
Store at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Immunology/Inflammation
Target COX
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Piroxicam - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
331.35 C15H13N3O4S 36322-90-4 4-Hydroxy-2-methyl-N-2-pyridinyl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide; 4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide

Structure Information of Piroxicam

Smiles OC(C(C=CC=C1)=C1S(N2C)(=O)=O)=C2C(NC3=NC=CC=C3)=O
InChI InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)

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Safety Data of Piroxicam

Hazard Symbols:Xn Risk Statements:R22 Safety Statements:S26;S36
Transport Information:UN 2811 HS Code: RTECS:DL0705000
WGK Germany:

Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:198-200°C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,66 mg/mL(199.18 mM);In vitro:Ethanol,1 mg/mL(3.01 mM);In vitro:Water,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:252-974-3
Optical Rotation: alpha:

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