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Clarithromycin

(CAS: 81103-11-9)

Suppliers of Clarithromycin

Company Name Email Tel Country
Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 0.96 Brand: Alfa Chemistry

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD60/100mg () USD96/200mg ()

Carbosynth Limited [email protected] +44 (1635) 578-444

Fax: +44 (1635) 579-444Purity: Brand:

Price and Availability: USD40/10g ()

Glentham Life Sciences [email protected] +44 (2033) 978-798

Fax: +44 (2033) 978-909Purity: Brand:

Liaoyang Zhongnuo Chemical & Industry Co., Ltd. [email protected] +86 (419) 330-6059 / 330-0938 China

Fax: +86 (419) 330-6899Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/100mg () USD96/200mg ()
Quality Control & MSDS Files: HNMR MSDS

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Price and Availability: USD69/100mg ()

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HPLC HNMR HPLC HNMR HPLC

Shandong Fangming Pharmaceutical Group Co., Ltd. [email protected],[email protected] +86 (530) 720-8439 / 519-8388 China

Fax: +86 (530) 720-1388Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD60/100mg () USD96/200mg ()

Sigma-Aldrich, Inc. [email protected] +86 (21) 6141-5566 / 800-819-3336 USA

Fax: Purity: Brand:

Price and Availability: USD71/100mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .99 Brand: TargetMol

Price and Availability: USD20/2mg () USD65/10mg () USD237/50mg () USD368/200mg ()

Tokyo Chemical Industry Co., Ltd. [email protected] 03-3668-0489 Japan

Fax: 03-3668-0520Purity: Brand:

Price and Availability: USD51/1g ()

Zhejiang Botai Chemical Co., Ltd. [email protected] +86 (576) 8412-6198 China

Fax: +86 (576) 8412-6210Purity: Brand:

Zhejiang Chemline industries Co., Ltd. [email protected],[email protected] +86 (571) 8720-7757 China

Fax: +86 (571) 8806-2298Purity: Brand:

Zhejiang Ouhua Chemical Imp. & Exp. Co., Ltd. [email protected] +86 (576) 8882-6717 China

Fax: +86 (576) 8882-8330Purity: Brand:

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Background Information of Clarithromycin

Clarithromycin is a macrolide antibiotic and a CYP3A4 inhibitor. Target: Antibacterial; CYP3A4 Clarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia (especially atypical pneumonias associated with Chlamydophila pneumoniae), skin and skin structure infections.

Solubility of Clarithromycin

Solubility Sources
DMSO 5 mg/mL; Water <1 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 25 mg/mL warming (33.42 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of Clarithromycin

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] MedChemexpress Co., Ltd.
[HPLC] [HNMR] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease Autophagy Anti-infection
Target Bacterial Autophagy Cytochrome P450
Research Area Infection
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Clarithromycin - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
747.95 C38H69NO13 81103-11-9 Biaxin;Biaxin XL;Clarosip;Klaricid; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-(((2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-14-ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione

Structure Information of Clarithromycin

Smiles C[[email protected]@](OC)(C[[email protected]](C([[email protected]@H]1C)=O)C)[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](C(O[[email protected]](CC)[[email protected]@](C)(O)[[email protected]@H]1O)=O)C)O[[email protected]@](O[[email protected]@H](C)[[email protected]@H]2O)([H])C[[email protected]@]2(C)OC)C)O[[email protected]@](O[[email protected]](C)C[[email protected]@H]3N(C)C)([H])[[email protected]@H]3O
InChI InChI=1S/C38H69NO13/c1-15-26-38(10,45)31(42)21(4)28(40)19(2)17-37(9,47-14)33(52-35-29(41)25(39(11)12)16-20(3)48-35)22(5)30(23(6)34(44)50-26)51-27-18-36(8,46-13)32(43)24(7)49-27/h19-27,29-33,35,41-43,45H,15-18H2,1-14H3/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1

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Other Form Products of Clarithromycin

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Safety Data of Clarithromycin

Hazard Symbols:Xn,Xi Risk Statements:22-36/37/38 Safety Statements:26-36
Transport Information: HS Code:29419000 RTECS:KF4997000
WGK Germany:

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:217-220°C
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:2339
BRN: Refractive Index: -92 ° (C=1, CHCl3)
Vapour: EINECS:
Optical Rotation: alpha:

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