Butoconazole (nitrate)
(CAS: 64872-77-1)
Suppliers of Butoconazole (nitrate)
Background Information of Butoconazole (nitrate)
Butoconazole nitrate is an anti-fungal agent.
Target: Antifungal
butoconazole 1-BSR is an effective and safe alternative to longer-term therapy with miconazole nitrate (seven days) for vulvovaginal candidiasis [1].
Solubility of Butoconazole (nitrate)
Storage Condition of Butoconazole (nitrate)
| Storage Condition |
Sources |
Quality Control and Spectral Data
Mechanism and Indications
Chemical Information
| M.Wt |
Formula |
CAS No. |
Synonyms |
| 474.79 |
C19H18Cl3N3O3S |
64872-77-1 |
1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenyl)sulfanyl-butyl]imidazole nitrate; 1-(4-(4-chlorophenyl)-2-((2,6-dichlorophenyl)thio)butyl)-1H-imidazole nitrate |
Structure Information of Butoconazole (nitrate)
| Smiles |
ClC1=C(C(Cl)=CC=C1)SC(CN2C=CN=C2)CCC3=CC=C(Cl)C=C3.O[N+]([O-])=O |
| InChI |
InChI=1S/C19H17Cl3N2S.HNO3/c20-15-7-4-14(5-8-15)6-9-16(12-24-11-10-23-13-24)25-19-17(21)2-1-3-18(19)22;2-1(3)4/h1-5,7-8,10-11,13,16H,6,9,12H2;(H,2,3,4) |
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Safety Data of Butoconazole (nitrate)
Chemical and Physical Properties
| Appearance:White to off-white Solid |
Melting point:159°C (dec.) |
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Reference
[1].Brown, D., M.R. Henzl, and R.H. Kaufman, Butoconazole nitrate 2% for vulvovaginal candidiasis. New, single-dose vaginal cream formulation vs. seven-day treatment with miconazole nitrate. Gynazole 1 Study Group. J Reprod Med, 1999. 44(11): p. 933-8.
[2].Heng, L.Z., Y. Chen, and T.C. Tan, Treatment of recurrent vulvo-vaginal candidiasis with sustained-released butoconazole pessary. Singapore Med J, 2012. 53(12): p. e269-71.
