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(R)-(-)-Phenylephrine (hydrochloride)

(CAS: 61-76-7)

Suppliers of (R)-(-)-Phenylephrine (hydrochloride)

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AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Boehringer Ingelheim GmbH [email protected] +49 6132-770 Germany

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD60/100mg () USD96/500mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD60/100mg () USD96/500mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

Mulberry Chemicals Pvt. Ltd. [email protected] +91 (22) 2871-0249 India

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HPLC HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Shenzhen Oriental Pharmaceutical Co., Ltd. [email protected] +86 (755) 8235-4524 China

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Syncozymes (Shanghai) Co., Ltd. [email protected],[email protected] +86 (21) 6818-7180 / 6818-7182 / 6818-7183 ex 825 / 802 China

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Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Xinxiang Tianfeng Fine Chemical Co., Ltd. [email protected] +86 (373) 251-3858 China

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Xuzhou Ruisai Technology Industry Co., Ltd. [email protected] +86 (526) 8776-8018 China

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Background Information of (R)-(-)-Phenylephrine (hydrochloride)

(R)-(-)-Phenylephrine hydrochloride is a phenylephrine (PE) and an α1-adrenoceptor agonist Target: α1- Adrenergic Receptor Phenylephrine (PE), an alpha-adrenergic agonist and promoter of hypertrophic growth in the ventricular myocyte, to activate the three best-characterized mitogen-activated protein kinase (MAPK) subfamilies, namely p38-MAPKs, SAPKs/JNKs (i.e.

Solubility of (R)-(-)-Phenylephrine (hydrochloride)

Solubility Sources
DMSO 40 mg/mL; Water 40 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 41 mg/mL (201.3 mM); Water41 mg/mL (201.3 mM); Ethanol41 mg/mL (201.3 mM) Selleck Chemicals LLC
Soluble to 100 mM in water and to 100 mM in DMSO Tocris Bioscience Inc.

Storage Condition of (R)-(-)-Phenylephrine (hydrochloride)

Storage Condition Sources
Desiccate at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways GPCR/G Protein
Target Adrenergic Receptor
Research Area Cardiovascular Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
(R)-(-)-Phenylephrine (hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
203.67 C9H14ClNO2 61-76-7 L(-)-Phenylephrine hydrochloride; (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride; 3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol; (R)-3-(1-hydroxy-2-(methylamino)ethyl)phenol hydrochloride

Structure Information of (R)-(-)-Phenylephrine (hydrochloride)

Smiles O[[email protected]@H](CNC)C1=CC(O)=CC=C1.Cl
InChI InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

Related Products

Other Form Products of (R)-(-)-Phenylephrine (hydrochloride)

Name CAS Formula Suppliers
(R)-(-)-Phenylephrine 59-42-7 C9H13NO2 10

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Safety Data of (R)-(-)-Phenylephrine (hydrochloride)

Hazard Symbols:Xn Risk Statements:R22;R36/37/38 Safety Statements:S26;S37/39
Transport Information: HS Code: RTECS:DO7525000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:143-145 °C(lit.)
Boiling point: Flash Point:
Water Solubility: >=10 g/100 mL at 21 ºC Solubility:In vitro:DMSO,41 mg/mL(201.3 mM);In vitro: Water,41 mg/mL(201.3 mM);In vitro:Ethanol,41 mg/mL(201.3 mM);
Density: Merck:7286
BRN: Refractive Index: -45.5 ° (C=1, H2O)
Vapour: EINECS:200-517-3
Optical Rotation: alpha: -47 º (c=2, H2O)

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