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Clorsulon

(CAS: 60200-06-8)

Suppliers of Clorsulon

Company Name Email Tel Country
AA Blocks LLC [email protected] +1 858-523-8231

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Airsea(Taizhou) Pharmaceutical Co., Ltd [email protected] +86-576-8057622, 8698002 CHINA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BLD Pharmatech [email protected] +86-21-61629022

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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Biotalk Co., Ltd. [email protected] +86 (21) 6501-2399 / 6504-0613 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD72/100mg () USD192/500mg ()

Hangzhou Mole's Science&Technology Co., Ltd. [email protected] +86 (571) 5688-0228 China

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Linhai Haixing Chemical Factory [email protected] +86 (576) 8833-6807 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD72/100mg () USD192/500mg ()
Quality Control & MSDS Files: HNMR

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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NGL Fine Chem Ltd. [email protected] +91 (22) 4053-9955 India

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD97/50mg (In stock) USD130/10mM/1mLIn DMSO (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC HNMR

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD72/100mg () USD192/500mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .99 Brand: TargetMol

Price and Availability: USD20/2mg () USD42/10mg () USD78/50mg () USD122/200mg ()

Zhejiang Shaxing Pharmaceutical & Chemical Co., Ltd. [email protected] +86 (576) 8568-6581 / 8568-6899 China

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Background Information of Clorsulon

Clorsulon is used in the treatment of Fasciola hepatica infections in calves and sheep. Target: Antiparasitic Clorsulon is a competitive inhibitor of both 3-phosphoglycorate and ATP and had a Ki of 0.29 mM, inhibits glucose utilization and acetate and propionate formation by mature Fasciola hepatica in vitro.

Solubility of Clorsulon

Solubility Sources
DMSO 76 mg/mL; Water <1 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 76 mg/mL (199.65 mM); Ethanol7 mg/mL (18.38 mM); Water<1 mg/mL (<1 mM); In vivo 1% DMSO+30% polyethylene glycol+1% Tween 8030 mg/mL Selleck Chemicals LLC

Storage Condition of Clorsulon

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Anti-infection
Target Parasite
Research Area Infection
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Clorsulon - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
380.66 C8H8Cl3N3O4S2 60200-06-8 Curatrem;L631529;MK401; 4-amino-6-(1,2,2-trichlorovinyl)benzene-1,3-disulfonamide

Structure Information of Clorsulon

Smiles O=S(C1=C(/C(Cl)=C(Cl)Cl)C=C(N)C(S(=O)(N)=O)=C1)(N)=O
InChI InChI=1S/C8H8Cl3N3O4S2/c9-7(8(10)11)3-1-4(12)6(20(14,17)18)2-5(3)19(13,15)16/h1-2H,12H2,(H2,13,15,16)(H2,14,17,18)

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:194-203°C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,76 mg/mL(199.65 mM);In vitro:Ethanol,7 mg/mL(18.38 mM);In vitro:Water,Insoluble;In vivo:Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):1% DMSO+30% polyethylene glycol+1% Tween 80For bes
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:262-100-2
Optical Rotation: alpha:

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