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Naftifine (hydrochloride)

(CAS: 65473-14-5)

Suppliers of Naftifine (hydrochloride)

Company Name Email Tel Country
BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: > 95% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD216/1g () USD660/5g ()

Changzhou Tianhua Pharmaceutical Co., Ltd. [email protected],[email protected] +86 (519) 8289-1186 China

Fax: +86 (519) 8289-9734Purity: Brand:

Datang (Hangzhou) Pharmachem Co., Ltd. [email protected] +86 (571) 8731-1096 China

Fax: +86 (571) 8693-2703Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD216/1g () USD660/5g ()
Quality Control & MSDS Files: HNMR LCMS MSDS

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand:

Price and Availability: USD110/50mg (In stock) USD670/500mg (In stock)
Quality Control & MSDS Files: HNMR HPLC HNMR HPLC

Shanghai Biosundrug Science & Technology Co., Ltd. [email protected] +86 (21) 3462-2192 China

Fax: +86 (21) 3462-2765Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD216/1g () USD660/5g ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .99 Brand: TargetMol

Price and Availability: USD62/5mg () USD117/10mg () USD216/25mg ()

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Background Information of Naftifine (hydrochloride)

Naftifine Hydrochloride is a synthetic, broad spectrum, antifungal agent. Target: Antifungal Naftifine exhibits an interesting in vitro spectrum of activity against dermatophytes (38 strains; minimal inhibitory concentration (MIC) range 0.1 to 0.2 mg/mL), aspergilli (6 strains; MIC range, 0.8 to 12.5 mg/mL), Sporothrix schenckii (2 strains; MICs, 0.8 and 1.5 mg/mL), and yeasts of the genus Candida (77 strains; MIC range, 1.5 to greater than 100 mg/mL) [1].

Solubility of Naftifine (hydrochloride)

Solubility Sources
DMSO <1 mg/mL; Water <1 mg/mL MedChemexpress Co., Ltd.
(25°C) * In vitro Ethanol 8 mg/mL (24.7 mM); DMSO<1 mg/mL (<1 mM); Water<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of Naftifine (hydrochloride)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.
[HNMR] [HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Anti-infection
Target Fungal
Research Area Infection
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Naftifine (hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
323.86 C21H22ClN 65473-14-5 (E)-N-Cinnamyl-N-methyl(1-naphthylmethyl)amine hydrochloride; (E)-N-methyl-N-(naphthalen-1-ylmethyl)-3-phenylprop-2-en-1-amine hydrochloride

Structure Information of Naftifine (hydrochloride)

Smiles CN(C/C=C/C1=CC=CC=C1)CC2=C3C=CC=CC3=CC=C2.[H]Cl
InChI InChI=1S/C21H21N.ClH/c1-22(16-8-11-18-9-3-2-4-10-18)17-20-14-7-13-19-12-5-6-15-21(19)20;/h2-15H,16-17H2,1H3;1H/b11-8+;

Related Products

Other Form Products of Naftifine (hydrochloride)

Name CAS Formula Suppliers
Naftifine (hydrochloride) 65473-14-5 C21H22ClN 6

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:172-175°C
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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