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Hydroxyzine

(CAS: 68-88-2)

Suppliers of Hydroxyzine

Company Name Email Tel Country
Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 0.96 Brand: Alfa Chemistry

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. s[email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: ≥98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD72/100mg () USD132/500mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD72/100mg () USD132/500mg ()

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD72/100mg () USD132/500mg ()

Yann Pharmachem Co., Ltd. [email protected] +86 (21) 6522-5530 China

Fax: +86 (21) 6522-5811Purity: Brand:

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Background Information of Hydroxyzine

Hydroxyzine is a histamine H1-receptor antagonist. Target: Histamine H1-Receptor Hydroxyzine inhibits carbachol (10 μM)-induced serotonin release by 34% at 10 μM, by 25% 1 μM and by 17% 0.1 μM in pretreated bladder slices for 60 min [1].

Solubility of Hydroxyzine

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Hydroxyzine

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways Immunology/Inflammation GPCR/G Protein
Target Histamine Receptor
Research Area Inflammation/Immunology
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Hydroxyzine - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
374.9 C21H27ClN2O2 68-88-2 2-[2-[4-[(4-Chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]ethanol; 1-(4-Chloro-alpha-phenylbenzyl)-4-((2-(2-hydroxyethoxy)ethyl)piperazine); 2-(2-(4-((4-chlorophenyl)(phenyl)methyl)piperazin-1-yl)ethoxy)ethanol

Structure Information of Hydroxyzine

Smiles ClC1=CC=C(C=C1)C(C2=CC=CC=C2)N3CCN(CCOCCO)CC3
InChI InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2

Related Products

Other Form Products of Hydroxyzine

Name CAS Formula Suppliers
Hydroxyzine (dihydrochloride) 2192-20-3 C21H29Cl3N2O2 13
Hydroxyzine (D4' dihydrochloride) 1219805-91-0 C21H25D4Cl3N2O2 2

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Ranitidine (hydrochloride) 66357-59-3 C13H23ClN4O3S 17
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Chemical and Physical Properties

Appearance: Melting point:190°C
Boiling point: Flash Point:
Water Solubility: < 700 mg/mL Solubility:Soluble in DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:200-693-1
Optical Rotation: alpha: yms2-[2-[4-[(4-Chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]ethanol; 1-(4-Chloro-alpha-phenylbenzyl)-4-((2-(2-hydroxyethoxy)ethyl)piperazine)

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