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Dehydrocostus Lactone

(CAS: 477-43-0)

Suppliers of Dehydrocostus Lactone

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand:

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Affix Scientific [email protected] +1-510-936-6647 USA

Fax: Purity: ≥98% Brand:

Price and Availability: USD750/1g (In stock)
Quality Control & MSDS Files: CoA MSDS

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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AvaChem Scientific LLC [email protected] +1 (210) 667-3815 USA

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BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: ≥95% Brand: BOC Sciences

Price and Availability: USD199/50mg (In stock) USD398/1g (In stock)

Baoji Herbest Bio-Tech Co., Ltd. [email protected]; [email protected]; [email protected] +86 (917) 888-8998 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD84/5mg () USD156/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD84/5mg () USD156/10mg ()

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD84/5mg () USD156/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD109/10mg () USD408/50mg ()

Zhongshang Pharmcare Bio-Tech Co., Ltd. [email protected] +86 (760) 8892-2139 China

Fax: +86 (760) 8674-5859Purity: Brand:

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Background Information of Dehydrocostus Lactone

Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.

Solubility of Dehydrocostus Lactone

Solubility Sources
10 mM in DMSO CHEMSCENE, LLC
10 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of Dehydrocostus Lactone

Storage Condition Sources
Up to one week at 4°C or six months at -20°C. Affix Scientific

MSDS Information

MSDS Sources
Affix Scientific

Quality Control and Spectral Data

QC Reports Sources
[CoA] Affix Scientific

Mechanism and Indications

Signaling Pathways Others
Target Others
Research Area Others
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Dehydrocostus Lactone - Not Found
Dehydrocostus Lactone - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
230.3 C15H18O2 477-43-0 (3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one; (3aS,6aR,9aR,9bS)-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one

Structure Information of Dehydrocostus Lactone

Smiles O=C(O[[email protected]@]([[email protected]@]1([H])C(CC[[email protected]@]21[H])=C)([H])[[email protected]@]3([H])CCC2=C)C3=C
InChI InChI=1S/C15H18O2/c1-8-4-7-12-10(3)15(16)17-14(12)13-9(2)5-6-11(8)13/h11-14H,1-7H2/t11-,12-,13-,14-/m0/s1

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Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,46 mg/mL(199.73 mM);In vitro:Ethanol,46 mg/mL(199.73 mM);In vitro:Water,Insoluble;
Density:1.09 Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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