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Dehydrocostus Lactone

(CAS: 477-43-0)

Suppliers of Dehydrocostus Lactone

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Affix Scientific [email protected] +1-510-936-6647 USA

Fax: Purity: ≥98% Brand:

Price and Availability: USD750/1g (In stock)
Quality Control & MSDS Files: CoA MSDS

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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AvaChem Scientific LLC [email protected] +1 (210) 667-3815 USA

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BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: ≥95% Brand: BOC Sciences

Price and Availability: USD199/50mg (In stock) USD398/1g (In stock)

Baoji Herbest Bio-Tech Co., Ltd. [email protected]; [email protected]; [email protected] +86 (917) 888-8998 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD84/5mg () USD156/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD84/5mg () USD156/10mg ()

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD84/5mg () USD156/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD109/10mg () USD408/50mg ()

Zhongshang Pharmcare Bio-Tech Co., Ltd. [email protected] +86 (760) 8892-2139 China

Fax: +86 (760) 8674-5859Purity: Brand:

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Background Information of Dehydrocostus Lactone

Dehydrocostus lactone (DHE), a natural sesquiterpene lactone, inhibits IKKβ activity, IκBα phosphorylation and degradation, coactivators p300 recruitments and p50/p65 NF-κB nuclear translocation, and their DNA binding activity on COX-2 promoter. It has anti-inflammatory, anti-ulcer, immunomodulatory and anti-tumor properties.

Solubility of Dehydrocostus Lactone

Solubility Sources
10 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of Dehydrocostus Lactone

Storage Condition Sources
Up to one week at 4°C or six months at -20°C. Affix Scientific

MSDS Information

MSDS Sources
Affix Scientific

Quality Control and Spectral Data

QC Reports Sources
[CoA] Affix Scientific

Mechanism and Indications

Signaling Pathways Others
Target Others
Research Area Others

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Dehydrocostus Lactone - Not Found
Dehydrocostus Lactone - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
230.3 C15H18O2 477-43-0 (3aS,6aR,9aR,9bS)-Decahydro-3,6,9-tris(methylene)azuleno[4,5-b]furan-2(3H)-one; (3aS,6aR,9aR,9bS)-3,6,9-trimethylenedecahydroazuleno[4,5-b]furan-2(9bH)-one

Structure Information of Dehydrocostus Lactone

Smiles O=C(O[[email protected]@]([[email protected]@]1([H])C(CC[[email protected]@]21[H])=C)([H])[[email protected]@]3([H])CCC2=C)C3=C
InChI InChI=1S/C15H18O2/c1-8-4-7-12-10(3)15(16)17-14(12)13-9(2)5-6-11(8)13/h11-14H,1-7H2/t11-,12-,13-,14-/m0/s1

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Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,46 mg/mL(199.73 mM);In vitro:Ethanol,46 mg/mL(199.73 mM);In vitro:Water,Insoluble;
Density:1.09 Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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