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(CAS: 1226781-44-7)

Suppliers of Omarigliptin

Company Name Email Tel Country
Active Biochem [email protected]; [email protected] 1-800-857-0985 (USA Toll Free#) USA

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Price and Availability: USD350/20mg ()

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

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BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

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Price and Availability: USD95/1mg ()

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Lancrix Chemicals. [email protected] 86 21 50817262 China

Fax: 86 21 57712035Purity: Brand:

Price and Availability: USD495/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD132/2mg () USD192/5mg ()
Quality Control & MSDS Files: HNMR NP-HPLC MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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ProbeChem [email protected] 86-21-80183644

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD132/2mg () USD192/5mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

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Toronto Research Chemicals Inc. [email protected] +1 (416) 665-9696 Canada

Fax: +1 (416) 665-4439Purity: Brand:

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Background Information of Omarigliptin

Omarigliptin (MK-3102) is a competitive, reversible inhibitor of DPP-4 (IC50 = 1.6 nM, Ki = 0.8 nM). It is highly selective over all proteases tested (IC50 > 67 μM), including QPP, FAP, PEP, DPP8, and DPP9 and has weak ion channel activity (IC50 > 30 μM at IKr, Caγ1.2, and Naγ1.5).

Solubility of Omarigliptin

Solubility Sources
10 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of Omarigliptin

Storage Condition Sources
4°C MedChemexpress Co., Ltd.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [NP-HPLC] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease
Target Dipeptidyl Peptidase
Research Area Metabolic Disease

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Omarigliptin - No Development Reported
Omarigliptin - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
398.43 C17H20F2N4O3S 1226781-44-7 MK3102;MK 3102;MK-3102; (2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H-pyran-3-amine

Structure Information of Omarigliptin

Smiles N[[email protected]@H]1[[email protected]@H](C2=CC(F)=CC=C2F)OC[[email protected]](N3CC4=NN(S(=O)(C)=O)C=C4C3)C1
InChI InChI=1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12)13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17-/m1/s1

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Name CAS Formula Suppliers

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Trelagliptin 865759-25-7 C18H20FN5O2 18
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Sitagliptin (phosphate monohydrate) 654671-77-9 C16H20F6N5O6P 22
DBPR108 1186426-66-3 C16H25FN4O2 7
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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,79 mg/mL(198.27 mM);In vitro:Water,Insoluble;In vitro:Ethanol,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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