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CTX-0294885

(CAS: 1439934-41-4)

Suppliers of CTX-0294885

Company Name Email Tel Country
Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 0.98 Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

Fax: 408-493-1801Purity: Brand:

Price and Availability: USD115/5mg ()

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD108/5mg () USD180/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

DC Chemicals [email protected]; [email protected] +86-21-58447131 China

Fax: +86-21-61642470Purity: Brand:

Price and Availability: USD550/100mg (In stock)

Lancrix Chemicals. [email protected] 86 21 50817262 China

Fax: 86 21 57712035Purity: Brand:

Price and Availability: USD428/50mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD108/5mg () USD180/10mg ()
Quality Control & MSDS Files: LCMS HNMR MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Price and Availability: USD120/5mg ()
Quality Control & MSDS Files: CoA HNMR LCMS MSDS

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD108/5mg () USD180/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD29/1mg () USD156/10mg () USD568/50mg ()

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Background Information of CTX-0294885

CTX-0294885 is a novel broad-spectrum kinase inhibitor. CTX-0294885 exhibits inhibitory activity against a broad range of kinases in vitro. Use of a quantitative proteomics approach confirmed the selectivity of CTx - 0294885 -bound beads for kinase enrichment. Large-scale CTX- 0294885 -based affinity purification followed by LC-MS/MS led to the identification of 235 protein kinases from MDA-MB-231 cells, including all members of the AKT family that had not been previously detected by other broad-spectrum kinase inhibitors. CTX- 0294885 represents a powerful new reagent for analysis of kinome signaling networks that may facilitate development of targeted therapeutic strategies.

Solubility of CTX-0294885

Solubility Sources
10 mM in DMSO CHEMSCENE, LLC
10 mM in DMSO MedChemexpress Co., Ltd.
Soluble in DMSO, not in water MedKoo Biosciences, Inc.

Storage Condition of CTX-0294885

Storage Condition Sources
4°C MedChemexpress Co., Ltd.
Storage condition:Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). Stock solution storage:0 - 4 C for short term (days to weeks), or -20 C for long term (months). Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. MedKoo Biosciences, Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.
MedKoo Biosciences, Inc.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.
[CoA] [HNMR] [LCMS] MedKoo Biosciences, Inc.

Mechanism and Indications

Signaling Pathways Others
Target Others
Research Area Others
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
CTX-0294885 - Not Found
CTX-0294885 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
437.93 C22H24ClN7O 1439934-41-4 CTX0294885;CTX 0294885; 2-((5-chloro-2-((4-(piperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)-N-methylbenzamide

Structure Information of CTX-0294885

Smiles O=C(NC)C1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCNCC4)C=C3)=NC=C2Cl
InChI InChI=1S/C22H24ClN7O/c1-24-21(31)17-4-2-3-5-19(17)28-20-18(23)14-26-22(29-20)27-15-6-8-16(9-7-15)30-12-10-25-11-13-30/h2-9,14,25H,10-13H2,1H3,(H,24,31)(H2,26,27,28,29)

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Chemical and Physical Properties

Appearance:light yellow to green yellow Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:>21.9mg/mL in DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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