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Lercanidipine (hydrochloride)

(CAS: 132866-11-6)

Suppliers of Lercanidipine (hydrochloride)

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AA Blocks LLC [email protected] +1 858-523-8231

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AbMole BioScience [email protected] 1-800-660-8580 USA

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Heta Pharm & Chem Co., Ltd. [email protected],[email protected] +86 (571) 8829-8691 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Quality Control & MSDS Files: HNMR LCMS MSDS

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Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Zhejiang Esun Chemical Co., Ltd. [email protected] +86 (571) 5628-6531 China

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Background Information of Lercanidipine (hydrochloride)

Lercanidipine hydrochloride is a calcium channel blocker of the dihydropyridine class. Target: Calcium Channel Lercanidipine is a calcium channel blocker of the dihydropyridine class, which works by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body.

Solubility of Lercanidipine (hydrochloride)

Solubility Sources
DMSO MedChemexpress Co., Ltd.
Soluble to 100 mM in DMSO and to 10 mM in ethanol Tocris Bioscience Inc.

Storage Condition of Lercanidipine (hydrochloride)

Storage Condition Sources
Desiccate at +4°C Tocris Bioscience Inc.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Membrane Transporter/Ion Channel
Target Calcium Channel
Research Area Cardiovascular Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Lercanidipine (hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
648.19 C36H42ClN3O6 132866-11-6 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester hydrochloride; 3-(1-((3,3-diphenylpropyl)(methyl)amino)-2-methylpropan-2-yl) 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride

Structure Information of Lercanidipine (hydrochloride)

Smiles O=C(C1=C(C)NC(C)=C(C(OC(C)(C)CN(CCC(C2=CC=CC=C2)C3=CC=CC=C3)C)=O)C1C4=CC=CC([N+]([O-])=O)=C4)OC.[H]Cl
InChI InChI=1S/C36H41N3O6.ClH/c1-24-31(34(40)44-6)33(28-18-13-19-29(22-28)39(42)43)32(25(2)37-24)35(41)45-36(3,4)23-38(5)21-20-30(26-14-9-7-10-15-26)27-16-11-8-12-17-27;/h7-19,22,30,33,37H,20-21,23H2,1-6H3;1H

Related Products

Other Form Products of Lercanidipine (hydrochloride)

Name CAS Formula Suppliers
Lercanidipine 100427-26-7 C36H41N3O6 14

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Safety Data of Lercanidipine (hydrochloride)

Hazard Symbols:T Risk Statements:R25 Safety Statements:S36/37;S45
Transport Information:UN 2811 HS Code: RTECS:
WGK Germany:

Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:175-177°C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,66 mg/mL(101.82 mM);In vitro:Ethanol,1 mg/mL(1.54 mM);In vitro:Water,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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