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Ropinirole (hydrochloride)

(CAS: 91374-20-8)

Suppliers of Ropinirole (hydrochloride)

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AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Chem-Cook Chemicals Ltd. [email protected] +86 (23) 6253-9363 / +86 13657620624 China

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Chongqing Yifutech Co., Ltd. [email protected] +86 (23) 6842-1858 / +86 13983604463 / 13068320173 China

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Jintan Shuibei Pharmchem Factory [email protected] +86 (519) 8255-1234 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD60/50mg () USD90/100mg ()
Quality Control & MSDS Files: LCMS HNMR

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD97/25mg (In stock) USD130/10mM/1mLIn DMSO (In stock) USD170/50mg (In stock)
Quality Control & MSDS Files: HPLC

Shaanxi Pioneer Biotech Co., Ltd. [email protected] +86 (29) 8438-5017 China

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Shanghai Amadis Bio-Technology Co., Ltd [email protected] (852)-2815 8172 CHINA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Shanghai T&W Pharmatech Co., Ltd. [email protected] +86 (21) 6155-1611 / 6155-1413 / 6155-1420 China

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Target Molecule Corp. [email protected] (857) 239-0968 USA

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Price and Availability: USD39/10mg () USD65/25mg () USD112/50mg ()

Tianjin Dongchang Chemical Industry Co., Ltd. [email protected] +86 (22) 2989-8890 / +86 13110020885 China

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Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Background Information of Ropinirole (hydrochloride)

Ropinirole hydrochloride(SKF101468 hydrochloride) a selective dopamine D2 receptor inhibitor with IC50 of 29 nM. Target: Dopamine D2 Receptor Ropinirole (50 mg/kg, i.p.) causes biphasic spontaneous locomotor activity in mice.

Solubility of Ropinirole (hydrochloride)

Solubility Sources
DMSO MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 10 mg/mL (33.68 mM); Water60 mg/mL (202.12 mM); Ethanol<1 mg/mL (<1 mM) Selleck Chemicals LLC
Soluble to 100 mM in water and to 50 mM in DMSO Tocris Bioscience Inc.

Storage Condition of Ropinirole (hydrochloride)

Storage Condition Sources
Desiccate at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.
[HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Neuronal Signaling GPCR/G Protein
Target Dopamine Receptor
Research Area Neurological Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Ropinirole (hydrochloride) - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
296.84 C16H25ClN2O 91374-20-8 SKF101468 hydrochloride;SKF 101468 hydrochloride;SKF-101468 hydrochloride; 4-(2-(dipropylamino)ethyl)indolin-2-one hydrochloride

Structure Information of Ropinirole (hydrochloride)

Smiles O=C1NC2=C(C(CCN(CCC)CCC)=CC=C2)C1.Cl
InChI InChI=1S/C16H24N2O.ClH/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15;/h5-7H,3-4,8-12H2,1-2H3,(H,17,19);1H

Related Products

Other Form Products of Ropinirole (hydrochloride)

Name CAS Formula Suppliers
Ropinirole 91374-21-9 C16H24N2O 6

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Safety Data of Ropinirole (hydrochloride)

Hazard Symbols:Xn,N,Xi Risk Statements:22-50/53-36/38 Safety Statements:36-60-61-37/39-26
Transport Information: HS Code: RTECS:NM3288250
WGK Germany:

Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:241-243°C
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:Water,60 mg/mL(202.12 mM);In vitro:DMSO,10 mg/mL(33.68 mM);In vitro:Ethanol,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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