• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

Exatecan (Mesylate)

(CAS: 169869-90-3)

Suppliers of Exatecan (Mesylate)

Company Name Email Tel Country
Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Price and Availability: USD298/1mg (In stock) USD998/10mg (In stock)

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD660/1mg () USD1176/5mg ()

Hangzhou Guangyuan Biotechnology Co., Ltd. [email protected]; [email protected] 0571-88690598 4001686671 CHINA

Fax: 0571-88690598Purity: > 98% Brand: RayStarBio

Price and Availability: USD800/5mg (In stock)

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD660/1mg () USD1176/5mg ()
Quality Control & MSDS Files: HNMR NP-HPLC LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD660/1mg () USD1176/5mg ()

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of Exatecan (Mesylate)

Exatecan Mesylate (DX-8951) is a totally synthetic analogue of the topoisomerase I-inhibitor camptothecin, which was synthesised to impart increased aqueous solubility, greater tumour efficacy, and less toxicity than camptothecin itself. IC50 value: Target: topoisomerase I Exatecan was given as i.v.

Solubility of Exatecan (Mesylate)

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Exatecan (Mesylate)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [NP-HPLC] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage
Target Topoisomerase
Research Area Cancer
Indications Pancreatic Cancer

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Exatecan (Mesylate) Daiichi Sankyo Inc. Pancreatic Cancer 2001/7/01 2005/4/01 Phase 3 Clinical
Exatecan (Mesylate) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
531.55 C25H26FN3O7S 169869-90-3 DX8951f;DX 8951f;DX-8951f; (1S,9S)-1-amino-9-ethyl-5-fluoro-9-hydroxy-4-methyl-2,3,12,15-tetrahydrobenzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-10,13(1H,9H)-dione methanesulfonate

Structure Information of Exatecan (Mesylate)

Smiles O=S(C)(O)=O.O=C1[[email protected]](O)(CC)C2=C(CO1)C(N3CC4=C5C6=C(CC[[email protected]@H]5N)C(C)=C(F)C=C6N=C4C3=C2)=O
InChI InChI=1S/C24H22FN3O4.CH4O3S/c1-3-24(31)14-6-18-21-12(8-28(18)22(29)13(14)9-32-23(24)30)19-16(26)5-4-11-10(2)15(25)7-17(27-21)20(11)19;1-5(2,3)4/h6-7,16,31H,3-5,8-9,26H2,1-2H3;1H3,(H,2,3,4)/t16-,24-;/m0./s1

Related Products

Other Form Products of Exatecan (Mesylate)

Name CAS Formula Suppliers
Exatecan 171335-80-1 C24H22FN3O4 9

Recommended Products in Same Target

Name CAS Formula Suppliers
Pirarubicin (Hydrochloride) 95343-20-7 C32H38ClNO12 8
Flumequine 42835-25-6 C14H12FNO3 17
Nemorubicin 108852-90-0 C32H37NO13 9
Amsacrine (hydrochloride) 54301-15-4 C21H20ClN3O3S 11
Ellipticine 519-23-3 C17H14N2 18
DOXO-EMCH 151038-96-9 C37H42N4O13 9
Topotecan (Hydrochloride) 119413-54-6 C23H24ClN3O5 28
Topotecan 123948-87-8 C23H23N3O5 9
Tirapazamine 27314-97-2 C7H6N4O2 14
Teniposide 29767-20-2 C32H32O13S 24
TAS-103 174634-08-3 C20H19N3O2 8
TAS-103 (dihydrochloride) 174634-09-4 C20H21Cl2N3O2 10
Pixantrone (dimaleate) 144675-97-8 C21H23N5O6 12
Pixantrone 144510-96-3 C17H19N5O2 10
Pirarubicin 72496-41-4 C32H37NO12 24
SN-38 86639-52-3 C22H20N2O5 31
Irinotecan (hydrochloride) 100286-90-6 C33H39ClN4O6 18
Exatecan 171335-80-1 C24H22FN3O4 9
Etoposide 33419-42-0 C29H32O13 29
Epirubicin (hydrochloride) 56390-09-1 C27H30ClNO11 26

Recommended Products in the Same Indication

Name CAS Formula Suppliers
Exatecan 171335-80-1 C24H22FN3O4 9
NLG-919 1402836-58-1 16
Talabostat (mesylate) 150080-09-4 C10H23BN2O6S 10
Rimantadine (hydrochloride) 1501-84-4 9
Dolastatin 10 110417-88-4 C42H68N6O6S 8
TAS-102 733030-01-8 C20H28Cl2F3N7O6 8

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:Soluble in DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy Exatecan (Mesylate) | Exatecan (Mesylate) IC50 | Exatecan (Mesylate) price | Exatecan (Mesylate) cost | Exatecan (Mesylate) solubility | Exatecan (Mesylate) purchase | Exatecan (Mesylate) manufacturer | Exatecan (Mesylate) research buy | Exatecan (Mesylate) order | Exatecan (Mesylate) MSDS | Exatecan (Mesylate) chemical structure | Exatecan (Mesylate) Storage condition | Exatecan (Mesylate) molecular weight | Exatecan (Mesylate) mw | Exatecan (Mesylate) datasheet | Exatecan (Mesylate) supplier | Exatecan (Mesylate) cell line | Exatecan (Mesylate) NMR | Exatecan (Mesylate) MS | Exatecan (Mesylate) IR | Exatecan (Mesylate) solubility | Exatecan (Mesylate) Safe information | Exatecan (Mesylate) Qc and Spectral Information | Exatecan (Mesylate) Clinical Information | Exatecan (Mesylate) Clinical Trial | Exatecan (Mesylate) Route of Synthesis | Exatecan (Mesylate) storage condition | Exatecan (Mesylate) diseases and conditions | Exatecan (Mesylate) flash point | Exatecan (Mesylate) boiling point | Exatecan (Mesylate) melting point | Exatecan (Mesylate) storage condition | Exatecan (Mesylate) brand