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Bevirimat

(CAS: 174022-42-5)

Suppliers of Bevirimat

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

Fax: Purity: Brand:

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Price and Availability: USD168/5mg (In stock)

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()

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Background Information of Bevirimat

Bevirimat(YK FH312; FH11327; MPC-4326) is an anti-HIV drug derived from a betulinic acid-like compound; is believed to inhibit HIV by a novel mechanism, so-called maturation inhibition. IC50 value: Target: Anti-HIV Like protease inhibitors, bevirimat and other maturation inhibitors interfere with protease processing of newly translated HIV polyprotein precursor, called gag.

Solubility of Bevirimat

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Bevirimat

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Anti-infection
Target HIV
Research Area Infection
Indications HIV-1 Infection HIV Infections

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Bevirimat Myrexis Inc. HIV-1 Infection 2008/11/01 Phase 2
Bevirimat Myrexis Inc. HIV Infections 2006/4/01 Phase 2
Bevirimat Myrexis Inc. HIV Infections 2008/5/01 Phase 2
Bevirimat Myrexis Inc. HIV Infections 2009/11/01 Phase 2

Chemical Information

M.Wt Formula CAS No. Synonyms
584.83 C36H56O6 174022-42-5 PA-457;MPC-4326;FH11327;YK FH312; (1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-((3-carboxy-3-methylbutanoyl)oxy)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysene-3a-carboxylic acid

Structure Information of Bevirimat

Smiles OC([[email protected]]1(CC[[email protected]]2C(C)=C)[[email protected]@]2([H])[[email protected]](CC[[email protected]@]3([H])[[email protected]]4(CC[[email protected]]5([H])[[email protected]@]3(CC[[email protected]](OC(CC(C)(C)C(O)=O)=O)C5(C)C)C)C)([H])[[email protected]@]4(C)CC1)=O
InChI InChI=1S/C36H56O6/c1-21(2)22-12-17-36(30(40)41)19-18-34(8)23(28(22)36)10-11-25-33(7)15-14-26(42-27(37)20-31(3,4)29(38)39)32(5,6)24(33)13-16-35(25,34)9/h22-26,28H,1,10-20H2,2-9H3,(H,38,39)(H,40,41)/t22-,23+,24-,25+,26-,28+,33-,34+,35+,36-/m0/s1

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Recommended Products in the Same Indication

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Etravirine 269055-15-4 C20H15BrN6O 18
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Maraviroc 376348-65-1 C29H41F2N5O 15
Elvitegravir 697761-98-1 C23H23ClFNO5 18
GS-7340 379270-37-8 C21H29N6O5P 14
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Delavirdine (mesylate) 147221-93-0 C23H32N6O6S2 15
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Amprenavir 161814-49-9 C25H35N3O6S 19
Tipranavir 174484-41-4 C31H33F3N2O5S 13

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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