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Rose Bengal (sodium salt)(1:2)

(CAS: 632-69-9)

Suppliers of Rose Bengal (sodium salt)(1:2)

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Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 0.96 Brand: Alfa Chemistry

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Background Information of Rose Bengal (sodium salt)(1:2)

Potent VGlut and vesicular monoamine transporter (VMAT) inhibitor (Ki values are 19 and 64 nM, respectively). Inhibits ATP dependent vesicular glutamate uptake (IC50 = 37 nM) and diminishes the amount of exocytotically released glutamate in synaptosomes. Decreases synaptic transmission in the dentate gyrus. Also stains exposed epithelium in the eye. Cell permeable.

Solubility of Rose Bengal (sodium salt)(1:2)

Solubility Sources
Soluble to 100 mM in water and to 50 mM in DMSO Tocris Bioscience Inc.

Storage Condition of Rose Bengal (sodium salt)(1:2)

Storage Condition Sources
Store at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways
Target
Research Area
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Rose Bengal (sodium salt)(1:2) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
1017.64 C20H2Cl4I4Na2O5 632-69-9 C.I. 45440; Rose Bengal sodium salt; Disodium 3,4,5,6-tetrachloro-2-(2,4,5,7-tetraiodo-6-oxido-3-oxoxanthen-9-yl)benzoate; sodium 2,3,4,5-tetrachloro-6-(2,4,5,7-tetraiodo-6-oxido-3-oxo-3H-xanthen-9-yl)benzoate

Structure Information of Rose Bengal (sodium salt)(1:2)

Smiles O=C([O-])C1=C(Cl)C(Cl)=C(Cl)C(Cl)=C1C2=C3C=C(I)C(C(I)=C3OC4=C2C=C(I)C([O-])=C4I)=O.[Na+].[Na+]
InChI InChI=1S/C20H4Cl4I4O5.2Na/c21-10-8(9(20(31)32)11(22)13(24)12(10)23)7-3-1-5(25)16(29)14(27)18(3)33-19-4(7)2-6(26)17(30)15(19)28;;/h1-2,29H,(H,31,32);;/q;2*+1/p-2

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Safety Data of Rose Bengal (sodium salt)(1:2)

Hazard Symbols:Xi Risk Statements:R36 Safety Statements:S26;S37/39
Transport Information: HS Code: RTECS:LM5920000
WGK Germany:3

Chemical and Physical Properties

Appearance: Melting point:>300°C
Boiling point: Flash Point:
Water Solubility: soluble Solubility:DMSO:50.88mg/mL;50mM;water:101.76mg/mL;100mM;
Density: Merck:14,8262
BRN:3645857 Refractive Index:
Vapour: EINECS:211-183-3
Optical Rotation: alpha:

Reference

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