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Tri(hydroxymethyl)aminomethane

(CAS: 77-86-1)

Suppliers of Tri(hydroxymethyl)aminomethane

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Adipogen Corporation [email protected] (858) 457-8383 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

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BioSpectra, Inc. [email protected] 717 992 1243 USA

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Epochem Co., Ltd. [email protected] +86 (21) 6760-1595 / 6760-1597 China

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Glentham Life Sciences [email protected] +44 (2033) 978-798

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Guangzhou Bio-Key Science-Tech Co., Ltd. [email protected] +86 (20) 8557-2027 / 8557-2636 / 8553-9023 China

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Hangzhou Longshan Chemical Co., Ltd. [email protected] +86 (571) 8805-6685 / 8806-6888 China

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Hangzhou Manwei Chemical Co., Ltd. [email protected] +86 (571) 8802-1612 / +86 13396532940 China

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Jiangyin Nijiaxiang Chemical Co., Ltd. [email protected] +86 (510) 8622-1606 / 8622-5314 China

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MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Nanjing Beyo Chemical Co., Ltd. [email protected] +86 (25) 8473-0627 / 8473-0637 China

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Nanjing Search Bio Tech Co., Ltd. [email protected],[email protected] +86 (25) 8168-2922 China

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Suzhou BEC Fine Chemicals Co., Ltd. [email protected] +86 (512) 6809-5917 / +86 13806207098 China

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Suzhou Yacoo Chemical Reagent Corporation [email protected],[email protected] +86 (512) 8718-2055 / +86 15995843646 China

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Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .995 Brand: TargetMol

Price and Availability: USD27/5mg () USD165/50mg () USD325/100mg ()

The Dow Chemical Company [email protected] +1 (989) 633-1706 USA

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Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Vitas-M [email protected] +7 (906) 781-2021 Russia

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Wuhan Benjamin Pharmaceutical Chemical Co., Ltd. [email protected] +86 (27) 5234-1789 China

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Zibo Xingzhilian Chemistry Co., Ltd. [email protected] +86 (311) 8201-6547 / 8201-2958 China

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Background Information of Tri(hydroxymethyl)aminomethane

Trometamol is a proton acceptor used to treat acidemia. It inhibits both isoforms of cyclooxygenases (COX1 and COX2), thereby blocking the conversion of arachidonic acid to pro-inflammatory pro-prostaglandins.

Solubility of Tri(hydroxymethyl)aminomethane

Solubility Sources
Soluble to 5000 mM in water Tocris Bioscience Inc.

Storage Condition of Tri(hydroxymethyl)aminomethane

Storage Condition Sources
Store at RT Tocris Bioscience Inc.

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways
Target
Research Area
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Tri(hydroxymethyl)aminomethane - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
121.14 C4H11NO3 77-86-1 THAM;Pehanorm;Trisamin;TAM

Structure Information of Tri(hydroxymethyl)aminomethane

Smiles OCC(CO)(N)CO
InChI InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2

Related Products

Other Form Products of Tri(hydroxymethyl)aminomethane

Name CAS Formula Suppliers
Tris (hydrochloride) 1185-53-1 C4H12ClNO3 7
Tris (Acetate) 6850-28-8 C6H15NO5 2

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Safety Data of Tri(hydroxymethyl)aminomethane

Hazard Symbols:Xi Risk Statements:R36/37/38 Safety Statements:S26;S37/39
Transport Information: HS Code:29221980 RTECS:TY2900000
WGK Germany:2

Chemical and Physical Properties

Appearance:white Melting point:167-172 °C(lit.)
Boiling point:219-220 ºC (10 mmHg) Flash Point:219-220°C/10mm
Water Solubility: 550 g/L (25 ºC) Solubility:In vitro:Water,24 mg/mL(198.11 mM);In vitro:DMSO,2 mg/mL(16.5 mM);In vitro:Ethanol,Insoluble;
Density: Merck:14,9772
BRN:741883 Refractive Index:
Vapour: EINECS:201-064-4
Optical Rotation: alpha:

Reference

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