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Thioperamide

(CAS: 106243-16-7)

Suppliers of Thioperamide

Company Name Email Tel Country
Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 95% Brand: BOC Sciences

Labinova AB [email protected] +46 (0)8 59032490 Europe

Fax: +46 (0)8 43743202Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

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Background Information of Thioperamide

Potent histamine H3 and H4 antagonist/inverse agonist. Ki values are 25 and 27 nM for human recombinant H3 and H4 receptors respectively. Blocks eosinophil shape change (IC50 = 1.4 μM) and chemotaxis (IC50 = 519 nM) induced by histamine. Freely crosses the blood-brain barrier. Also available as part of the Histamine H3 Receptor Tocriset™.

Solubility of Thioperamide

Solubility Sources

Storage Condition of Thioperamide

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MSDS Information

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Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways
Target
Research Area
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Thioperamide - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
292.44 C15H24N4S 106243-16-7 MR 12842;MR-12842;MR12842; N-cyclohexyl-4-(1H-imidazol-5-yl)piperidine-1-carbothioamide

Structure Information of Thioperamide

Smiles S=C(N1CCC(C2=CN=CN2)CC1)NC3CCCCC3
InChI InChI=1S/C15H24N4S/c20-15(18-13-4-2-1-3-5-13)19-8-6-12(7-9-19)14-10-16-11-17-14/h10-13H,1-9H2,(H,16,17)(H,18,20)

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Chemical and Physical Properties

Appearance:white Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:ethanol:29.24mg/mL;100mM;DMSO:29.24mg/mL;100mM;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Reference

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