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Moxidectin

(CAS: 113507-06-5)

Suppliers of Moxidectin

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand:

Price and Availability: USD11/1mg ()

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD60/10mg () USD180/50mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Hangzhou Holypharm Biotech Co., Ltd. [email protected],[email protected] +86 (571) 8717-6852 / +86 18205813359 China

Fax: +86 (571) 8735-7695Purity: Brand:

Maxchemco Co., Ltd. [email protected],[email protected] +86 (21) 5107-9223 / +86 18611691717 China

Fax: +86 (21) 3332-1268Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD60/10mg () USD180/50mg ()
Quality Control & MSDS Files: LCMS HNMR MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD60/10mg () USD180/50mg ()

Taizhou Crene Biotechnology Co., Ltd. [email protected] +86 (576) 8881-3233 / 8820-5808 / +86 13396860566 China

Fax: +86 (576) 8822-9589Purity: Brand:

Taizhou Hikong Chemical Co., Ltd. [email protected],[email protected] +86 18967213045 / +86 13957694715 China

Fax: +86 (580) 603-4626Purity: Brand:

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD25/1mg () USD83/5mg () USD112/10mg () USD198/25mg ()

Zhejiang Hisoar Pharm.Co., Ltd. [email protected] +86 (576) 8882-8045 / 8882-9063 / 8886-1267 China

Fax: +86 (576) 8886-1260 / 8882-8228Purity: Brand:

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Background Information of Moxidectin

Moxidectin(ProHeart 6; CL301423; Cydectin) is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms. IC50 value: Target: Anti-parasitic Moxidectin is a semisynthetic derivative of nemadectin, which is produced by fermentation by Streptomyces cyano-griseus.

Solubility of Moxidectin

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Moxidectin

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Anti-infection
Target Parasite
Research Area Infection
Indications Onchocerciasis

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Moxidectin World Health Organization Onchocerciasis 2009/4/01 2012/5/01 Phase 3 Clinical
Moxidectin Pfizer; World Health Organization Onchocerciasis 2011/4/01 2011/4/01 Phase 2 Clinical
Moxidectin - Phase 3

Chemical Information

M.Wt Formula CAS No. Synonyms
639.82 C37H53NO8 113507-06-5 milbemycin B

Structure Information of Moxidectin

Smiles C[[email protected]]1([H])[[email protected]](/C(C)=C/C(C)C)([H])O[[email protected]]2(C/C1=NOC)C[[email protected]](OC3=O)([H])C[[email protected]](C/C=C(C)/C[[email protected]](C)([H])/C=C/C=C4[[email protected]@]([[email protected]]([[email protected]@H]5O)([H])OC/4)(O)[[email protected]@]3([H])C=C5C)([H])O2
InChI InChI=1S/C37H53NO8/c1-21(2)14-25(6)33-26(7)31(38-42-8)19-36(46-33)18-29-17-28(45-36)13-12-23(4)15-22(3)10-9-11-27-20-43-34-32(39)24(5)16-30(35(40)44-29)37(27,34)41/h9-12,14,16,21-22,26,28-30,32-34,39,41H,13,15,17-20H2,1-8H3/b10-9+,23-12+,25-14+,27-11+,38-31+/t22-,26-,28+,29-,30-,32+,33+,34+,36-,37+/m0/s1

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,100 mg/mL(156.29 mM);In vitro:Ethanol,100 mg/mL(156.29 mM);In vitro:Water,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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