• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

VT-464 (racemate)

(CAS: 1375603-36-3)

Suppliers of VT-464 (racemate)

Company Name Email Tel Country
Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD332/5mg () USD475/10mg () USD1425/50mg () USD1995/100mg ()

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()
Quality Control & MSDS Files: MSDS CoA LCMS

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of VT-464 (racemate)

VT-464 racemate is the racemate form of VT-464, which is a potent CYP17 lyase inhibitor(h-Lyase IC50=69 nM)inhibition. IC50 value: 69 nM(VT-464, h-CYP17 Lyase) [1] Target: CYP17 Lyase inhibitor in vitro: VT-464, a non-steroidal small molecule inhibits androgen production without mineralocorticoid excess or cortisol depletion by selective inhibition of CYP17 17,20-lyase.

Solubility of VT-464 (racemate)

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of VT-464 (racemate)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[CoA] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease
Target Cytochrome P450
Research Area Cancer
Indications Castration-resistant Prostate Cancer

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
VT-464 (racemate) Viamet Pharmaceuticals, Inc. Castration-resistant Prostate Cancer 2013/12/06 Phase 2 Clinical
VT-464 (racemate) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
399.34 C18H17F4N3O3 1375603-36-3 VT464 racemate;VT 464 racemate; 1-(6,7-bis(difluoromethoxy)naphthalen-2-yl)-2-methyl-1-(1H-1,2,3-triazol-4-yl)propan-1-ol

Structure Information of VT-464 (racemate)

Smiles FC(F)OC1=C(OC(F)F)C=C(C=CC(C(C2=CNN=N2)(C(C)C)O)=C3)C3=C1
InChI InChI=1S/C18H17F4N3O3/c1-9(2)18(26,15-8-23-25-24-15)12-4-3-10-6-13(27-16(19)20)14(28-17(21)22)7-11(10)5-12/h3-9,16-17,26H,1-2H3,(H,23,24,25)

Related Products

Other Form Products of VT-464 (racemate)

Name CAS Formula Suppliers
VT-464 1610537-15-9 C18H17F4N3O3 5
VT-464 (R enantiomer) 1375603-38-5 C18H17F4N3O3 4

Recommended Products in Same Target

Name CAS Formula Suppliers
Dafadine-A 1065506-69-5 C23H25N3O3 7
VT-464 1610537-15-9 C18H17F4N3O3 5
Isosilybin 72581-71-6 C25H22O10 4
Memantine (hydrochloride) 41100-52-1 C12H22ClN 18
Clarithromycin 81103-11-9 C38H69NO13 18
(+)-Ketoconazole 142128-59-4 C26H28Cl2N4O4 4
(+)-Ketoconazole 142128-59-4 C26H28Cl2N4O4 13
Galangin 548-83-4 13
Bergapten 484-20-8 C12H8O4 9
Naringin 10236-47-2 C27H32O14 19
Diosmetin 520-34-3 C16H12O6 12
Fenofibrate 49562-28-9 C20H21ClO4 25
Bergaptol 486-60-2 C11H6O4 4
Talarozole (R enantiomer) 870093-23-5 C21H23N5S 5
Choline Fenofibrate 856676-23-8 C22H28ClNO5 10
Talarozole 201410-53-9 C21H23N5S 8
Isavuconazole 241479-67-4 C22H17F2N5OS 8
Cobicistat 1004316-88-4 C40H53N7O5S2 9
Methoxsalen 298-81-7 C12H8O4 13
TAK-700 (R-form) 752243-39-3 C18H17N3O2 1

Recommended Products in the Same Indication

Name CAS Formula Suppliers
VT-464 1610537-15-9 C18H17F4N3O3 5

Chemical and Physical Properties

Appearance: Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy VT-464 (racemate) | VT-464 (racemate) IC50 | VT-464 (racemate) price | VT-464 (racemate) cost | VT-464 (racemate) solubility | VT-464 (racemate) purchase | VT-464 (racemate) manufacturer | VT-464 (racemate) research buy | VT-464 (racemate) order | VT-464 (racemate) MSDS | VT-464 (racemate) chemical structure | VT-464 (racemate) Storage condition | VT-464 (racemate) molecular weight | VT-464 (racemate) mw | VT-464 (racemate) datasheet | VT-464 (racemate) supplier | VT-464 (racemate) cell line | VT-464 (racemate) NMR | VT-464 (racemate) MS | VT-464 (racemate) IR | VT-464 (racemate) solubility | VT-464 (racemate) Safe information | VT-464 (racemate) Qc and Spectral Information | VT-464 (racemate) Clinical Information | VT-464 (racemate) Clinical Trial | VT-464 (racemate) Route of Synthesis | VT-464 (racemate) storage condition | VT-464 (racemate) diseases and conditions | VT-464 (racemate) flash point | VT-464 (racemate) boiling point | VT-464 (racemate) melting point | VT-464 (racemate) storage condition | VT-464 (racemate) brand