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(CAS: 186139-09-3)

Suppliers of MSI-1436

Company Name Email Tel Country
Aladdin [email protected] 400 620 6333 China

Fax: 021 5102 6000Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD600/1mg () USD1140/5mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD600/1mg () USD1140/5mg ()
Quality Control & MSDS Files: HNMR HNMR MSDS

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD600/1mg () USD1140/5mg ()

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Background Information of MSI-1436

Solubility of MSI-1436

Solubility Sources
10 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of MSI-1436

Storage Condition Sources
Store in a tightly closed container, in a cool and dry place. MedChemexpress Co., Ltd.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease
Target Phosphatase
Research Area Endocrinology
Indications Diabetes Mellitus Obesity

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
MSI-1436 Genaera Corporation Diabetes Mellitus Obesity 2008/1/21 2009/4/01 Phase 1 Clinical
MSI-1436 - Phase 1

Chemical Information

M.Wt Formula CAS No. Synonyms
685.06 C37H72N4O5S 186139-09-3 MSI 1436;MSI1436;Aminosterol 1436;Aminosterol1436;Aminosterol-1436;Trodusquemine; (3R,6R)-6-((3S,5R,7R,8R,9S,10S,13R,14S,17R)-3-((3-((4-((3-aminopropyl)amino)butyl)amino)propyl)amino)-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-methylheptan-3-yl hydrogen sulfate

Structure Information of MSI-1436

Smiles NCCCNCCCCNCCCN[[email protected]@H]1C[[email protected]@](C[[email protected]@H](O)[[email protected]]2([H])[[email protected]]3([H])CC[[email protected]@]4(C)[[email protected]@]2([H])CC[[email protected]@]4([[email protected]](C)CC[[email protected]@H](OS(=O)(O)=O)C(C)C)[H])([H])[[email protected]]3(C)CC1
InChI InChI=1S/C37H72N4O5S/c1-26(2)34(46-47(43,44)45)13-10-27(3)30-11-12-31-35-32(15-17-37(30,31)5)36(4)16-14-29(24-28(36)25-33(35)42)41-23-9-22-40-20-7-6-19-39-21-8-18-38/h26-35,39-42H,6-25,38H2,1-5H3,(H,43,44,45)/t27-,28-,29+,30-,31+,32+,33-,34?,35+,36+,37-/m1/s1

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Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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