• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

XEN445

(CAS: 1515856-92-4)

Suppliers of XEN445

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand: AOBIOUS INC

Price and Availability: USD21/1mg ()

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Price and Availability: USD180/2mg () USD350/5mg () USD600/10mg ()

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD332/5mg () USD475/10mg () USD1425/50mg () USD1995/100mg ()

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

Fax: 408-493-1801Purity: Brand:

Price and Availability: USD115/5mg () USD460/25mg ()

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD124/5mg () USD216/10mg ()

Lancrix Chemicals. [email protected] 86 21 50817262 China

Fax: 86 21 57712035Purity: Brand:

Price and Availability: USD266/25mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD124/5mg () USD216/10mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD185/5mg (In stock)

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD124/5mg () USD216/10mg ()

Sigma-Aldrich, Inc. [email protected] +86 (21) 6141-5566 / 800-819-3336 USA

Fax: Purity: Brand:

Price and Availability: USD79/5mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD75/2mg () USD124/5mg () USD345/25mg () USD604/50mg ()

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of XEN445

XEN445 is a potent and selective EL inhibitor(IC50=0.237 uM), that showed good ADME and PK properties, and demonstrated in vivo efficacy in raising plasma HDLc concentrations in mice. IC50 value: 0.237 uM [1] Target: Endothelial lipase inhibitor XEN445 can be readily prepared in good yield from commercial available chemicals, which was selected for further evaluation of this series of EL inhibitors.

Solubility of XEN445

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of XEN445

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Others
Target Others
Research Area Cardiovascular Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
XEN445 - Not Found
XEN445 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
366.33 C18H17F3N2O3 1515856-92-4 XEN 445;XEN-445; (S)-2-(3-(pyridin-2-ylmethoxy)pyrrolidin-1-yl)-5-(trifluoromethyl)benzoic acid

Structure Information of XEN445

Smiles O=C(O)C1=CC(C(F)(F)F)=CC=C1N2C[[email protected]@H](OCC3=NC=CC=C3)CC2
InChI InChI=1S/C18H17F3N2O3/c19-18(20,21)12-4-5-16(15(9-12)17(24)25)23-8-6-14(10-23)26-11-13-3-1-2-7-22-13/h1-5,7,9,14H,6,8,10-11H2,(H,24,25)/t14-/m0/s1

Related Products

Other Form Products of XEN445

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
(R)-(+)-Etomoxir (sodium salt) 828934-41-4 C15H18ClNaO4 9
Dictamine 484-29-7 C12H9NO2 4
3,3',5-Triiodo-L-thyronine (sodium) 55-06-1 C15H11I3NNaO4 14
Fabomotizole (hydrochloride) 173352-39-1 C15H22ClN3O2S 5
FPH2 957485-64-2 C14H16ClN5O2S 8
α-Tocopherol (phosphate) 38976-17-9 C29H51O5P 4
BAMB-4 891025-25-5 C15H12N2O2 5
LDN-27219 312946-37-5 C20H16N4O2S2 6
ISO-1 478336-92-4 C12H13NO4 11
Aurothioglucose 12192-57-3 C6H11AuO5S 7
Oxybenzone 131-57-7 C14H12O3 34
ITX3 347323-96-0 C22H17N3OS 8
Cardiogreen 3599-32-4 C43H47N2NaO6S2 5
Skp2 Inhibitor C1 432001-69-9 C18H13BrN2O4S2 8
INH1 313553-47-8 C18H16N2OS 10
PF6-AM 1268491-69-5 C33H31BO12 4
Disperse Blue 148 52239-04-0 C19H19N5O4S 5
Solvent Blue 35 17354-14-2 C22H26N2O2 5
CID-797718 370586-05-3 C12H11NO3 7
CP-640186 (hydrochloride) 591778-70-0 C30H36ClN3O3 7

Recommended Products in the Same Indication

Name CAS Formula Suppliers

Chemical and Physical Properties

Appearance:nigger-brown Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy XEN445 | XEN445 IC50 | XEN445 price | XEN445 cost | XEN445 solubility | XEN445 purchase | XEN445 manufacturer | XEN445 research buy | XEN445 order | XEN445 MSDS | XEN445 chemical structure | XEN445 Storage condition | XEN445 molecular weight | XEN445 mw | XEN445 datasheet | XEN445 supplier | XEN445 cell line | XEN445 NMR | XEN445 MS | XEN445 IR | XEN445 solubility | XEN445 Safe information | XEN445 Qc and Spectral Information | XEN445 Clinical Information | XEN445 Clinical Trial | XEN445 Route of Synthesis | XEN445 storage condition | XEN445 diseases and conditions | XEN445 flash point | XEN445 boiling point | XEN445 melting point | XEN445 storage condition | XEN445 brand