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Thio-TEPA

(CAS: 52-24-4)

Suppliers of Thio-TEPA

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AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand: AOBIOUS INC

Price and Availability: USD5/1mg ()

Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 98%,USP32 Brand: Alfa Chemistry

BOC Sciences [email protected] 1-631-504-6093

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Carbosynth Limited [email protected] +44 (1635) 578-444

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Price and Availability: USD180/250mg ()

LKT Laboratories Inc. [email protected] 1-888-LKT-LABS, 1-888-558-5227 USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD60/100mg ()

Shanghai Hengrui International Trading Co., Ltd. [email protected] +86 (21) 5981-1275 China

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Sigma-Aldrich, Inc. [email protected] +86 (21) 6141-5566 / 800-819-3336 USA

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Taizhou Crene Biotechnology Co., Ltd. [email protected] +86 (576) 8881-3233 / 8820-5808 / +86 13396860566 China

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Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD20/5mg () USD79/25mg () USD178/100mg () USD315/200mg ()

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Background Information of Thio-TEPA

Thio-TEPA(Thioplex; Tiofosfamid) is an alkylating agent used to treat cancer, this molecule features tetrahedral phosphorus and is structurally akin to phosphate. IC50 value: Target: DNA alkylator Thiotepa has been previously used in the palliation of a wide variety of neoplastic diseases.

Solubility of Thio-TEPA

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Thio-TEPA

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage
Target DNA Alkylator/Crosslinker
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Thio-TEPA - Launched

Chemical Information

M.Wt Formula CAS No. Synonyms
189.22 C6H12N3PS 52-24-4 N,N',N''-Triethylenethiophosphoramide; Thio-TEPA; Tris(1-aziridinyl)phosphine sulfide; tri(aziridin-1-yl)phosphine sulfide

Structure Information of Thio-TEPA

Smiles S=P(N1CC1)(N2CC2)N3CC3
InChI InChI=1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2

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Safety Data of Thio-TEPA

Hazard Symbols:T+ Risk Statements:R28;R45;R46 Safety Statements:S28;S36/37;S45;S53
Transport Information:UN 2811 HS Code: RTECS:SZ2975000
WGK Germany:3

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:54-57 °C
Boiling point: Flash Point:
Water Solubility: 19 g/100 mL (25 ºC) Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:200-135-7
Optical Rotation: alpha:

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