Thio-TEPA
(CAS: 52-24-4)
Background Information of Thio-TEPA
Thio-TEPA(Thioplex; Tiofosfamid) is an alkylating agent used to treat cancer, this molecule features tetrahedral phosphorus and is structurally akin to phosphate.
IC50 value:
Target: DNA alkylator
Thiotepa has been previously used in the palliation of a wide variety of neoplastic diseases.
Storage Condition of Thio-TEPA
| Storage Condition |
Sources |
Quality Control and Spectral Data
Mechanism and Indications
Clinical Information
| Product Name |
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Indications |
Start Date |
End Date |
Phase |
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Thio-TEPA
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Launched |
Chemical Information
| M.Wt |
Formula |
CAS No. |
Synonyms |
| 189.22 |
C6H12N3PS |
52-24-4 |
N,N',N''-Triethylenethiophosphoramide; Thio-TEPA; Tris(1-aziridinyl)phosphine sulfide; tri(aziridin-1-yl)phosphine sulfide |
Structure Information of Thio-TEPA
| Smiles |
S=P(N1CC1)(N2CC2)N3CC3 |
| InChI |
InChI=1S/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2 |
Related Products
Other Form Products of Thio-TEPA
| Name |
CAS |
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Recommended Products in Same Target
Recommended Products in the Same Indication
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CAS |
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Chemical and Physical Properties
| Appearance:White to off-white Solid |
Melting point:54-57 °C |
| Boiling point: |
Flash Point: |
| Water Solubility: 19 g/100 mL (25 ºC) |
Solubility: |
| Density: |
Merck: |
| BRN: |
Refractive Index: |
| Vapour: |
EINECS:200-135-7 |
| Optical Rotation: |
alpha: |
