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Satraplatin

(CAS: 129580-63-8)

Suppliers of Satraplatin

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Abcam [email protected] (888) 77-ABCAM (22226) USA

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD420/5mg () USD600/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Clearsynth Labs Limited [email protected] Worldwide Helpline No. +1-415-685-4395; US & Canada (Toll-free) : +1-800-650-8239; Europe : +44-20-3286-0885; India : +91-22-26355700 India

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LKT Laboratories Inc. [email protected] 1-888-LKT-LABS, 1-888-558-5227 USA

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Price and Availability: USD200/5mg (Out of stock) USD320/10mg (Out of stock) USD1028/50mg (Out of stock)

Lianyungang Guike Pharmaceutical Co., ltd. [email protected] +86 (518) 8607-0808 / 8607-0855 China

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Lianyungang Guiyuan Chempharm Co., Ltd [email protected] 0518-80682158 80682157 CHINA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD420/5mg () USD600/10mg ()
Quality Control & MSDS Files: HNMR LCMS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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ProbeChem [email protected] 86-21-80183644

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD420/5mg () USD600/10mg ()

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Background Information of Satraplatin

Satraplatin(BMS182751; BMY45594; JM216) is a platinum-based antineoplastic agent that is under investigation as one treatment of patients with advanced prostate cancer who have failed previous chemotherapy. IC50 value: Target: DNA alkylator/crosslinker Satraplatin is the first orally active platinum-based chemotherapeutic drug.

Solubility of Satraplatin

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Satraplatin

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage
Target DNA Alkylator/Crosslinker
Research Area Cancer
Indications Lung Cancer Advanced Solid Tumors Tumors Prostate Cancer

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Satraplatin Agennix Lung Cancer 2006/8/30 Phase 2 Clinical
Satraplatin Southern Europe New Drug Organization Advanced Solid Tumors 2010/10/11 Phase 1 Clinical
Satraplatin Agennix Tumors 2005/7/28 Phase 1 Clinical
Satraplatin Agennix Prostate Cancer 2003/9/30 Phase 3 Clinical
Satraplatin - Phase 3

Chemical Information

M.Wt Formula CAS No. Synonyms
500.28 C10H22Cl2N2O4Pt 129580-63-8 Bis(acetato-O)amminedichloro(cyclohexanamine)-pt; Platinum (lV) cis-dichloro-trans-bis(acetato-O)ammine(cyclohexanamine);

Structure Information of Satraplatin

Smiles Cl[Pt](OC(C)=O)(Cl)OC(C)=O.NC1CCCCC1.N
InChI InChI=1S/C6H13N.2C2H4O2.2ClH.H3N.Pt/c7-6-4-2-1-3-5-6;2*1-2(3)4;;;;/h6H,1-5,7H2;2*1H3,(H,3,4);2*1H;1H3;/q;;;;;;+4/p-4

Related Products

Other Form Products of Satraplatin

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LY-2584702 (free base) 1082949-67-4 C21H19F4N7 12
LY-2584702 (tosylate salt) 1082949-68-5 C28H27F4N7O3S 14
Motolimod 926927-61-9 C28H34N4O2 13
NVP-HSP990 934343-74-5 C20H18FN5O2 18
Auristatin PE 149606-27-9 C39H67N5O6 5
Dolastatin 10 110417-88-4 C42H68N6O6S 8

Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:DMSO: ≥ 33 mg/mL
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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