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(CAS: 187389-52-2)

Suppliers of Z-VAD(OMe)-FMK

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A.G. Scientific, Inc. [email protected] 858 452 9925 USA

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AbMole BioScience [email protected] 1-800-660-8580 USA

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Price and Availability: USD380/5mg (In stock)

Abcam [email protected] (888) 77-ABCAM (22226) USA

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Adipogen Corporation [email protected] (858) 457-8383 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Price and Availability: USD32/1mg ()

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Price and Availability: USD55/1mg (In stock)

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

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Price and Availability: USD665/5mg ()

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD66/1mg () USD180/5mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Price and Availability: USD99/1mg ()

EMD Millipore USA

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Price and Availability: USD214/1mg ()

LC Laboratoies [email protected] +1-781-937-0777 +1-800-937-3720 in US and Canada only USA

Fax: +1-781-938-5420Purity: >99% Brand:

Price and Availability: USD59/1mg (COMING SOON) USD185/5mg (COMING SOON) USD275/10mg (COMING SOON) USD588/25mg (COMING SOON) USD997/100mg (COMING SOON)

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD66/1mg () USD180/5mg ()
Quality Control & MSDS Files: HNMR LCMS NP-HPLC MSDS

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD147/1mg (In stock)

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD66/1mg () USD180/5mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: 97% Brand: TargetMol

Price and Availability: USD38/1mg () USD115/5mg () USD190/10mg () USD343/25mg () USD575/50mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Price and Availability: USD215/1mg ()

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Background Information of Z-VAD(OMe)-FMK

Z-VAD(OMe)-FMK is a cell-permeable, pan-caspase inhibitor.

Solubility of Z-VAD(OMe)-FMK

Solubility Sources
Soluble in DMSO. LC Laboratoies
DMSO 90 mg/ml; Water <1 mg/ml MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO93 mg/mL (198 mM); Water<1 mg/mL (<1 mM); Ethanol24 mg/mL warming (51 mM); DMF84 mg/mL; * Z-VAD-FMK will racemize in DMSO, water and ethanol. Selleck Chemicals LLC

Storage Condition of Z-VAD(OMe)-FMK

Storage Condition Sources
Store at or below -20 oC. LC Laboratoies

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] [NP-HPLC] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Apoptosis
Target Caspase
Research Area Cancer

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Z-VAD(OMe)-FMK - Not Found
Z-VAD(OMe)-FMK - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
467.4879 C22H30FN3O7 187389-52-2 Z-Val-Ala-Asp(OMe)-FMK

Structure Information of Z-VAD(OMe)-FMK

Smiles O=C(CF)[[email protected]](CC(OC)=O)NC([[email protected]](C)NC([[email protected]](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O
InChI InChI=1S/C22H30FN3O7/c1-13(2)19(26-22(31)33-12-15-8-6-5-7-9-15)21(30)24-14(3)20(29)25-16(17(27)11-23)10-18(28)32-4/h5-9,13-14,16,19H,10-12H2,1-4H3,(H,24,30)(H,25,29)(H,26,31)/t14-,16-,19-/m0/s1

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,93 mg/mL(198.93 mM);In vitro:Water, Insoluble;In vitro:Ethanol,Insolublewarmed;In vivo:Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):2% DMSO+35 %PEG 300+2%Tween 80+ddH2OFor best result
Density:1.214±0.06 g/cm3 (20 ºC 760 Torr), Calc.* Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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