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INH1

(CAS: 313553-47-8)

Suppliers of INH1

Company Name Email Tel Country
BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD98/10mg () USD306/50mg ()

EMD Millipore USA

Fax: Purity: Brand:

Price and Availability: USD451/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD98/10mg () USD306/50mg ()
Quality Control & MSDS Files: HNMR LCMS

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Price and Availability: USD149/10mg ()

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD122/10mg (In stock)

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD98/10mg () USD306/50mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .995 Brand: TargetMol

Price and Availability: USD78/10mg () USD150/25mg () USD225/50mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

Price and Availability: USD155/10mg ()

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Background Information of INH1

INH1 is a small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cell growth in culture and in animal. IC50 value: 10-21 uM (GI50 in human breast cancer cell lines) [1] Target: Hec1 inhibitor Treating cells with INH1 triggered reduction of kinetochore-bound Hec1 as well as global Nek2 protein level, consequently leading to metaphase chromosome misalignment, spindle aberrancy, and eventual cell death.

Solubility of INH1

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of INH1

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Others
Target Others
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
INH1 - Not Found
INH1 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
308.4 C18H16N2OS 313553-47-8 IBT13131; N-(4-(2,4-dimethylphenyl)thiazol-2-yl)benzamide

Structure Information of INH1

Smiles O=C(NC1=NC(C2=CC=C(C)C=C2C)=CS1)C3=CC=CC=C3
InChI InChI=1S/C18H16N2OS/c1-12-8-9-15(13(2)10-12)16-11-22-18(19-16)20-17(21)14-6-4-3-5-7-14/h3-11H,1-2H3,(H,19,20,21)

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density:1.239±0.06 g/cm3 (20 ºC 760 Torr), Calc.* Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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