• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

T-5224

(CAS: 530141-72-1)

Suppliers of T-5224

Company Name Email Tel Country
AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Price and Availability: USD280/5mg ()

Alfa Chemistry [email protected] 1-201-478-8534 USA

Fax: 1-516-927-0118Purity: 0.96 Brand: Alfa Chemistry

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD100/5mg (In stock) USD150/10mg (In stock)

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

Fax: 408-493-1801Purity: Brand:

Price and Availability: USD145/5mg ()

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD120/5mg () USD180/10mg ()

DC Chemicals [email protected]; [email protected] +86-21-58447131 China

Fax: +86-21-61642470Purity: Brand:

Price and Availability: USD750/100mg (In stock)

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD120/5mg () USD180/10mg ()
Quality Control & MSDS Files: HNMR LCMS HNMR MSDS

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD120/5mg () USD180/10mg ()

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of T-5224

T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1, attenuates lipopolysaccharide-induced liver injury in mice. IC50 value: Target: c-Fos/AP1 inhibitor in vitro: T-5224 was converted to its acyl O-glucuronide (G2) by UGT1A1 and UGT1A3 and to its hydroxyl O-glucuronide (G3) by several UGTs, but it was not metabolized by the P450s [2]. in vivo: Administration of T-5224 (300 mg kg(-1), p.o.) after intraperitoneal injection of LPS imparted appreciable protection against acute elevations in serum levels of TNFα, HMGB1, ALT/AST as well as in liver tissue levels of MIP-1α and MCP-1, and reduced the lethality (27 %) [1].

Solubility of T-5224

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of T-5224

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease
Target MMP
Research Area Others
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
T-5224 - Not Found
T-5224 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
517.53 C29H27NO8 530141-72-1 T5224;T 5224; 3-(5-(4-(cyclopentyloxy)-2-hydroxybenzoyl)-2-((3-hydroxybenzo[d]isoxazol-6-yl)methoxy)phenyl)propanoic acid

Structure Information of T-5224

Smiles OC1=NOC2=CC(COC3=C(CCC(O)=O)C=C(C(C4=C(O)C=C(OC5CCCC5)C=C4)=O)C=C3)=CC=C21
InChI InChI=1S/C29H27NO8/c31-24-15-21(37-20-3-1-2-4-20)8-10-22(24)28(34)19-6-11-25(18(14-19)7-12-27(32)33)36-16-17-5-9-23-26(13-17)38-30-29(23)35/h5-6,8-11,13-15,20,31H,1-4,7,12,16H2,(H,30,35)(H,32,33)

Related Products

Other Form Products of T-5224

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
TAPI-1 163847-77-6 C26H37N5O5 6
Doxycycline (hyclate) 24390-14-5 C22H25ClN2O8 15
Doxycycline (hydrochloride) 10592-13-9 C24H33ClN2O10 10
NSC 405020 7497-07-6 C12H15Cl2NO 12
Edaravone 89-25-8 C10H10N2O 19
Astragaloside IV 84687-43-4 C41H68O14 13
GM6001 142880-36-2 C20H28N4O4 16
(-)-Epigallocatechin 970-74-1 C15H14O7 9
Stigmasterol 83-48-7 C29H48O 14
Incyclinide 15866-90-7 C19H17NO7 5
Batimastat (sodium salt) 130464-84-5 C23H30N3NaO4S2 5
Batimastat 130370-60-4 C23H31N3O4S2 15
Arctigenin 7770-78-7 C21H24O6 9
Marimastat 154039-60-8 C15H29N3O5 8
CTS-1027 193022-04-7 C19H20ClNO6S 5
Isoginkgetin 548-19-6 C32H22O10 7
GI254023X 260264-93-5 C21H33N3O4 4
PNU-248686A 341498-89-3 C22H19ClNaO5S2+ 3
SB-3CT 292605-14-2 C15H14O3S2 6
CL-82198 307002-71-7 C17H22N2O3 4

Recommended Products in the Same Indication

Name CAS Formula Suppliers

Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy T-5224 | T-5224 IC50 | T-5224 price | T-5224 cost | T-5224 solubility | T-5224 purchase | T-5224 manufacturer | T-5224 research buy | T-5224 order | T-5224 MSDS | T-5224 chemical structure | T-5224 Storage condition | T-5224 molecular weight | T-5224 mw | T-5224 datasheet | T-5224 supplier | T-5224 cell line | T-5224 NMR | T-5224 MS | T-5224 IR | T-5224 solubility | T-5224 Safe information | T-5224 Qc and Spectral Information | T-5224 Clinical Information | T-5224 Clinical Trial | T-5224 Route of Synthesis | T-5224 storage condition | T-5224 diseases and conditions | T-5224 flash point | T-5224 boiling point | T-5224 melting point | T-5224 storage condition | T-5224 brand