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(CAS: 75629-57-1)

Suppliers of Oncrasin-1

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AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Background Information of Oncrasin-1

Oncrasin-1 is a potent and effective anticancer inhibitor that kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations; also led to abnormal aggregation of PKCι in nucleus of sensitive cells but not in resistant cells. IC50 value: 1.0 μM(A549, K-ras 12H and p53 Wt) [1] Target: human lung cancer cells with K-Ras mutation; K-Ras/PKCiota pathway inhibitor in vitro: effectively kills various human lung cancer cells with K-Ras mutations at low or submicromolar concentrations.

Solubility of Oncrasin-1

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of Oncrasin-1

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways GPCR/G Protein
Target Ras
Research Area Cancer

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Oncrasin-1 - Not Found
Oncrasin-1 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
269.73 C16H12ClNO 75629-57-1 Oncrasin 1;Oncrasin1; 1-(4-chlorobenzyl)-1H-indole-3-carbaldehyde

Structure Information of Oncrasin-1

Smiles O=CC1=CN(CC(C=C2)=CC=C2Cl)C3=CC=CC=C31
InChI InChI=1S/C16H12ClNO/c17-14-7-5-12(6-8-14)9-18-10-13(11-19)15-3-1-2-4-16(15)18/h1-8,10-11H,9H2

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Chemical and Physical Properties

Appearance:Light yellow to earth yellow Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:Soluble in DMSO > 10 mM
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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