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iCRT 14

(CAS: 677331-12-3)

Suppliers of iCRT 14

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Price and Availability: USD133/10mg ()

Axon Medchem BV [email protected];[email protected] +31 50 3118007 Netherlands

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Price and Availability: USD162/10mg (In Stock)

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Price and Availability: USD298/25mg (In stock)

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD84/5mg () USD144/10mg ()

Carbosynth Limited [email protected] +44 (1635) 578-444

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Price and Availability: USD140/5mg ()

Hello Bio Inc. [email protected] +1-609-683-7500 USA

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Price and Availability: USD128/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD84/5mg () USD144/10mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Background Information of iCRT 14

iCRT 14 is a novel potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). IC50 value: 40.3 nM [1] Target: Wnt inhibitor Thought to directly influence the interaction between β-catenin and TCF4.

Solubility of iCRT 14

Solubility Sources
Soluble to 75 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of iCRT 14

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Stem Cell/Wnt
Target Wnt
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
iCRT 14 - Not Found
iCRT 14 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
375.44 C21H17N3O2S 677331-12-3 iCRT14;iCRT-14; (Z)-5-((2,5-dimethyl-1-(pyridin-3-yl)-1H-pyrrol-3-yl)methylene)-3-phenylthiazolidine-2,4-dione

Structure Information of iCRT 14

Smiles O=C(S/1)N(C2=CC=CC=C2)C(C1=CC3=C(C)N(C(C)=C3)C4=CN=CC=C4)=O
InChI InChI=1S/C21H17N3O2S/c1-14-11-16(15(2)23(14)18-9-6-10-22-13-18)12-19-20(25)24(21(26)27-19)17-7-4-3-5-8-17/h3-13H,1-2H3/b19-12-

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Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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