Tolazoline
(CAS: 59-98-3)
Background Information of Tolazoline
Tolazoline(NSC35110; Imidaline) is a non-selective competitive α-adrenergic receptor antagonist.
IC50 value:
Target: α-adrenoceptor antagonist
Tolazoline can be synthesized by the heterocyclation of the ethyl ester of iminophenzylacetic acid with ethylene diamine, which forms the desired product.
Storage Condition of Tolazoline
| Storage Condition |
Sources |
Quality Control and Spectral Data
Mechanism and Indications
Clinical Information
| Product Name |
Sponsor & Collaborators |
Indications |
Start Date |
End Date |
Phase |
|
Tolazoline
|
University of California, Davis |
Erectile Dysfunction
|
2007/12/13 |
2008/3/01 |
No Development Reported |
|
Tolazoline
|
- |
|
|
|
Launched |
Chemical Information
| M.Wt |
Formula |
CAS No. |
Synonyms |
| 160.22 |
C10H12N2 |
59-98-3 |
2-Benzylimidazoline; 2-Benzyl-4,5-dihydro-1H-imidazole; 4,5-Dihydro-2-(phenylmethyl)-1H-imidazole; 2-benzyl-4,5-dihydro-1H-imidazole |
Structure Information of Tolazoline
| Smiles |
C1(CC2=NCCN2)=CC=CC=C1 |
| InChI |
InChI=1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12) |
Related Products
Other Form Products of Tolazoline
Recommended Products in Same Target
Recommended Products in the Same Indication
Safety Data of Tolazoline
Chemical and Physical Properties
| Appearance: |
Melting point:66-69 °C(lit.) |
| Boiling point: |
Flash Point: |
| Water Solubility: |
Solubility:Soluble in DMSO, not in water |
| Density: |
Merck:13,9583 |
| BRN: |
Refractive Index: |
| Vapour: |
EINECS:200-448-9 |
| Optical Rotation: |
alpha: |
