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(CAS: 307510-92-5)

Suppliers of CFTR(inh)-172

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

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Price and Availability: USD80/5mg (In stock)

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

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BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD70/5mg () USD116/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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Price and Availability: USD65/5mg ()

EMD Millipore USA

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J&K Scientific Ltd. [email protected];[email protected] 400-666-7788 / +86 10 8284 8833 China

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Price and Availability: RMB1634/5mg (ship in 4-6 weeks) RMB6523/25mg (ship in 4-6 weeks)

Matrix Scientific [email protected] Orders: 800-733-0244 (US & CAN),All other calls: 803-788-9494 USA

Fax: Orders: 800-580-6330 (US & CAN), All other faxes: 803-788-9419Purity: Brand:

Price and Availability: USD378/1g ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD70/5mg () USD116/10mg ()
Quality Control & MSDS Files: NP-HPLC MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

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Price and Availability: USD145/10mg ()

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD147/10mg (In stock) USD470/50mg (In stock)
Quality Control & MSDS Files: HPLC HPLC

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD70/5mg () USD116/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD59/2mg () USD98/10mg () USD319/50mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Price and Availability: USD159/10mg ()

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Background Information of CFTR(inh)-172

CFTR(inh)-172 is an reversibly inhibitor of CFTR short-circuit current in less than 2 minutes in a voltage-independent manner with Ki approximately 300 nM.

Solubility of CFTR(inh)-172

Solubility Sources
Soluble to 100 mM in DMSO MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 82 mg/mL (200.29 mM); Water<1 mg/mL (<1 mM); Ethanol<1 mg/mL (<1 mM) Selleck Chemicals LLC

Storage Condition of CFTR(inh)-172

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[NP-HPLC] MedChemexpress Co., Ltd.
[HPLC] Selleck Chemicals LLC

Mechanism and Indications

Signaling Pathways Membrane Transporter/Ion Channel
Target CFTR
Research Area Others

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
CFTR(inh)-172 - Not Found
CFTR(inh)-172 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
409.4 C18H10F3NO3S2 307510-92-5 CFTR Inhibitor-172;CFTRinh-172; (Z)-4-((4-oxo-2-thioxo-3-(3-(trifluoromethyl)phenyl)thiazolidin-5-ylidene)methyl)benzoic acid

Structure Information of CFTR(inh)-172

Smiles S=C(S/1)N(C2=CC=CC(C(F)(F)F)=C2)C(C1=CC3=CC=C(C=C3)C(O)=O)=O
InChI InChI=1S/C18H10F3NO3S2/c19-18(20,21)12-2-1-3-13(9-12)22-15(23)14(27-17(22)26)8-10-4-6-11(7-5-10)16(24)25/h1-9H,(H,24,25)/b14-8-

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Safety Data of CFTR(inh)-172

Hazard Symbols:Xi,N Risk Statements:36/37/38-43-50/53 Safety Statements:26-36/37-60-61
Transport Information: HS Code: RTECS:
WGK Germany:

Chemical and Physical Properties

Appearance:Light yellow to yellow Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,82 mg/mL(200.29 mM);In vitro:Water,Insoluble;In vitro:Ethanol,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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