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AGN 196996

(CAS: 958295-17-5)

Suppliers of AGN 196996

Company Name Email Tel Country
Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD332/5mg ()

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD850/5mg () USD1200/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD850/5mg () USD1200/10mg ()
Quality Control & MSDS Files: LCMS

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD850/5mg () USD1200/10mg ()

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Background Information of AGN 196996

AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). IC50 value: 2 nM(Ki) Target: RARα antagonist AGN 196996 shows no activity in transactivation assays, but instead block the gene transcriptional activity induced by ATRA and other RAR agonists.

Solubility of AGN 196996

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of AGN 196996

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Metabolic Enzyme/Protease
Target RAR/RXR
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
AGN 196996 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
482.32 C24H20BrNO5 958295-17-5 AGN196996;AGN-196996; 4-(3-bromo-4-ethoxy-5-(4-methylbenzoyl)benzamido)benzoic acid

Structure Information of AGN 196996

Smiles BrC1=CC(C(NC2=CC=C(C(O)=O)C=C2)=O)=CC(C(C3=CC=C(C)C=C3)=O)=C1OCC
InChI InChI=1S/C24H20BrNO5/c1-3-31-22-19(21(27)15-6-4-14(2)5-7-15)12-17(13-20(22)25)23(28)26-18-10-8-16(9-11-18)24(29)30/h4-13H,3H2,1-2H3,(H,26,28)(H,29,30)

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
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Vapour: EINECS:
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