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AK-7

(CAS: 420831-40-9)

Suppliers of AK-7

Company Name Email Tel Country
Abcam [email protected] (888) 77-ABCAM (22226) USA

Fax: (877) 774-8286 / (617) 577-4201Purity: Brand:

Price and Availability: USD401/25mg ()

Axon Medchem BV [email protected];[email protected] +31 50 3118007 Netherlands

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Price and Availability: USD108/10mg (In Stock)

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

Fax: 408-493-1801Purity: Brand:

Price and Availability: USD90/5mg ()

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD132/10mg () USD420/50mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Price and Availability: USD59/5mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD132/10mg () USD420/50mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

Santa Cruz Biotechnology, Inc. [email protected] Toll Free: 800-457-3801 Phone: 214-902-3900 USA

Fax: 214-358-6070Purity: Brand:

Price and Availability: USD72/5mg ()

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD132/10mg () USD420/50mg ()

Sigma-Aldrich, Inc. [email protected] +86 (21) 6141-5566 / 800-819-3336 USA

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Price and Availability: USD77/5mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

Price and Availability: USD135/10mg ()

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Background Information of AK-7

AK-7 is a selective and brain-permeable SIRT2 inhibitor; is neuroprotective in Huntington disease mouse models. IC50 value: Target: SIRT2 AK-7 treated R6/2 mice performed significantly better than vehicle treated littermates on the accelerating rotarod at 8 and 11 weeks of age.

Solubility of AK-7

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of AK-7

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage Epigenetics
Target Sirtuin
Research Area Neurological Disease
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
AK-7 - Not Found
AK-7 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
437.35 C19H21BrN2O3S 420831-40-9 AK 7;AK7; 3-(azepan-1-ylsulfonyl)-N-(3-bromophenyl)benzamide

Structure Information of AK-7

Smiles O=S(N1CCCCCC1)(C2=CC(C(NC3=CC(Br)=CC=C3)=O)=CC=C2)=O
InChI InChI=1S/C19H21BrN2O3S/c20-16-8-6-9-17(14-16)21-19(23)15-7-5-10-18(13-15)26(24,25)22-11-3-1-2-4-12-22/h5-10,13-14H,1-4,11-12H2,(H,21,23)

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density:1.469±0.06 g/cm3 (20 ºC 760 Torr), Calc.* Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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