• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

MIM1

(CAS: 509102-00-5)

Suppliers of MIM1

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand:

Price and Availability: USD15/1mg ()

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: ≥98% Brand: BOC Sciences

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()
Quality Control & MSDS Files: HNMR

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD420/5mg () USD600/10mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

Fax: +1 (636) 207-7683Purity: Brand:

VDM BIOCHEMICALS,Inc. [email protected] 1-440-786-9400 USA

Fax: 1-440-786-9410Purity: Brand:

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of MIM1

MIM1 is a selective small molecule inhibitor of Mcl-1(IC50= 4.8 uM) that overcomes Mcl-1-dependent leukemia cell survival. IC50 value: 4.8 uM Target: Mcl-1 MIM1 effectively competed with FITC-MCL-1 SAHBA and FITC-BID BH3 for MCL-1ΔNΔC binding with respective IC50s of 4.7 and 4.8 μM, the compound showed no capacity to displace FITC-BID BH3 from BCL-XLΔC (IC50>50 μM), mirroring the selectivity of MCL-1 SAHBD. Although MCL-1 SAHBD was a 30 to 60-fold more potent competitor for MCL-1ΔNΔC binding than MIM1, the MCL-1 selective small molecule is one-seventh the size of the stapled peptide and exhibits an IC50 for its target (4.8 μM) that is only 7.5-fold less than that of chemically-optimized ABT-737 for BCL-XLΔC (0.63 μM) upon competition with FITC-BID BH3.

Solubility of MIM1

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of MIM1

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources
[HNMR] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Apoptosis
Target Bcl-2 Family
Research Area Cancer
Indications

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
MIM1 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
347.43 C17H21N3O3S 509102-00-5 MIM 1;MIM-1;Inhibitor of Mcl-1; 4-((E)-(((Z)-2-(cyclohexylimino)-4-methylthiazol-3(2H)-yl)imino)methyl)benzene-1,2,3-triol

Structure Information of MIM1

Smiles OC1=C(O)C(/C=N/N2/C(SC=C2C)=N/C3CCCCC3)=CC=C1O
InChI InChI=1S/C17H21N3O3S/c1-11-10-24-17(19-13-5-3-2-4-6-13)20(11)18-9-12-7-8-14(21)16(23)15(12)22/h7-10,13,21-23H,2-6H2,1H3/b18-9+,19-17-

Related Products

Other Form Products of MIM1

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
713492-66-1 5
Gossypol (acetic acid) 12542-36-8 C32H34O10 19
Marinopyrrole A 1227962-62-0 C22H12Cl4N2O4 6
WEHI-539 1431866-33-9 C31H29N5O3S2 13
Gambogic Acid 2752-65-0 C38H44O8 17
ABT-199 1257044-40-8 C45H50ClN7O7S 24
(±)-Apogossypol 475-56-9 C28H30O6 5
Gossypol 303-45-7 C30H30O8 25
AT-101 90141-22-3 C30H30O8 16
BAM7 331244-89-4 C21H19N5O2S 22
SZ4TA2 406231-90-1 C28H32N4O5S2 1
TW-37 877877-35-5 C33H35NO6S 17
HA14-1 65673-63-4 C17H17BrN2O5 17
Obatoclax 803712-79-0 C21H23N3O4S 16
ABT-737 852808-04-9 C42H45ClN6O5S2 20
Navitoclax 923564-51-6 C47H55ClF3N5O6S3 17
Bax inhibitor peptide V5 579492-81-2 C27H50N6O6S 9
A-1331852 1430844-80-6 C38H38N6O3S 13
A-1155463 1235034-55-5 C35H32FN5O4S2 12
Bz 423 216691-95-1 C27H21ClN2O2 8

Recommended Products in the Same Indication

Name CAS Formula Suppliers

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:DMSO:34.74mg/mL;100mM;ethanol:6.95mg/mL;20mM;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy MIM1 | MIM1 IC50 | MIM1 price | MIM1 cost | MIM1 solubility | MIM1 purchase | MIM1 manufacturer | MIM1 research buy | MIM1 order | MIM1 MSDS | MIM1 chemical structure | MIM1 Storage condition | MIM1 molecular weight | MIM1 mw | MIM1 datasheet | MIM1 supplier | MIM1 cell line | MIM1 NMR | MIM1 MS | MIM1 IR | MIM1 solubility | MIM1 Safe information | MIM1 Qc and Spectral Information | MIM1 Clinical Information | MIM1 Clinical Trial | MIM1 Route of Synthesis | MIM1 storage condition | MIM1 diseases and conditions | MIM1 flash point | MIM1 boiling point | MIM1 melting point | MIM1 storage condition | MIM1 brand