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(CAS: 1536200-31-3)

Suppliers of GNE-9605

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

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Price and Availability: USD150/5mg (In stock)

Active Biochem [email protected]; [email protected] 1-800-857-0985 (USA Toll Free#) USA

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Price and Availability: USD120/5mg ()

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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Apexbio Technology LLC [email protected] +1-832-696-8203 USA

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Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

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BOC Sciences [email protected] 1-631-504-6093

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Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD150/5mg () USD250/10mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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Price and Availability: USD150/5mg ()

ProbeChem [email protected] 86-21-80183644

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Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

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Price and Availability: USD197/5mg (In stock)

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Price and Availability: USD150/5mg () USD250/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD87/2mg () USD119/5mg () USD298/25mg () USD637/100mg ()

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Background Information of GNE-9605

GNE-9605 is a highly potent and selective leucine-rich repeat kinase 2 (LRRK2) inhibitor with Ki and IC50 of 2 nM and 19 nM, respectively.

Solubility of GNE-9605

Solubility Sources
DMSO 60 mg/ml MedChemexpress Co., Ltd.

Storage Condition of GNE-9605

Storage Condition Sources
4°C MedChemexpress Co., Ltd.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Autophagy
Target LRRK2
Research Area Neurological Disease

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
GNE-9605 - Not Found
GNE-9605 - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
449.83 C17H20ClF4N7O 1536200-31-3 GNE 9605;GNE9605;N2-(5-chloro-1-((3S,4S)-3-fluoro-1-(oxetan-3-yl)piperidin-4-yl)-1H-pyrazol-4-yl)-N4-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine; N2-(5-chloro-1-((3S,4S)-3-fluoro-1-(oxetan-3-yl)piperidin-4-yl)-1H-pyrazol-4-yl)-N4-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine

Structure Information of GNE-9605

Smiles FC(C1=CN=C(NC2=C(Cl)N([[email protected]@H]3[[email protected]@H](F)CN(C4COC4)CC3)N=C2)N=C1NC)(F)F
InChI InChI=1S/C17H20ClF4N7O/c1-23-15-10(17(20,21)22)4-24-16(27-15)26-12-5-25-29(14(12)18)13-2-3-28(6-11(13)19)9-7-30-8-9/h4-5,9,11,13H,2-3,6-8H2,1H3,(H2,23,24,26,27)/t11-,13-/m0/s1

Related Products

Other Form Products of GNE-9605

Name CAS Formula Suppliers

Recommended Products in Same Target

Name CAS Formula Suppliers
CZC-25146 1191911-26-8 C22H25FN6O4S 11
CZC-25146 (hydrochloride) 1330003-04-7 C22H25FN6O4S 9
GNE0877 1374828-69-9 C14H16F3N7 16
GNE-7915 1351761-44-8 C19H21F4N5O3 19
HG-10-102-01 1351758-81-0 C17H20ClN5O3 11
GSK2578215A 1285515-21-0 C24H18FN3O2 20
LRRK2-IN-1 1234480-84-2 C31H38N8O3 19
JH-II-127 1700693-08-8 C19H21ClN6O3 14
CZC-54252 1191911-27-9 C22H25ClN6O4S 13
PF-06447475 1527473-33-1 C17H15N5O 15
MLi-2 1627091-47-7 C21H25N5O2 6
PFE-360 1527475-61-1 C16H16N6O 0
Lu AF58786 1632368-13-8 C19H16N6 0
GNE-7915 (tosylate) C26H29F4N5O6S 0
CZC-25146 (hydrochloride) 1330003-04-7 C22H26ClFN6O4S 6
GNE-09605 1536200-31-3 C17H20ClF4N7O 0

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,89 mg/mL(197.85 mM);In vitro:Ethanol,12 mg/mLwarmed(26.67 mM);In vitro:Water,Insoluble;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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