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(CAS: 156722-18-8)

Suppliers of Rostafuroxin

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AOBIOUS INC [email protected] (508) 306-0937 USA

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Price and Availability: USD17/1mg () USD72/5mg ()

AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

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CHEMSCENE, LLC [email protected] 732-484-9848 USA

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Price and Availability: USD162/10mg () USD702/50mg ()

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Lancrix Chemicals. [email protected] 86 21 50817262 China

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MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

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Price and Availability: USD162/10mg () USD702/50mg ()
Quality Control & MSDS Files: HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

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ProbeChem [email protected] 86-21-80183644

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Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

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Target Molecule Corp. [email protected] (857) 239-0968 USA

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Price and Availability: USD42/1mg () USD102/5mg () USD158/10mg () USD285/25mg () USD525/50mg ()

Tocris Bioscience Inc. [email protected]; [email protected] +1 (636) 207-7651 USA

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Background Information of Rostafuroxin

Na+/K+ ATPase modulator. Inhibits the Normalizes renal Na+/K+ ATPase pump function in mutant adducin- and endogenous ouabain-dependent forms of hypertension. Reduces blood pressure in Milan hypertensive rats. Controls mania-like behaviors in Myshkin mice having a Na+/K+ ATPase α3 subunit mutation. Antagonizes the effects of Ouabain (Cat.No. 1076) on myogenic tone and Ca2+ signaling in rat hippocampal neurons.

Solubility of Rostafuroxin

Solubility Sources
100 mM in DMSO MedChemexpress Co., Ltd.

Storage Condition of Rostafuroxin

Storage Condition Sources
4°C MedChemexpress Co., Ltd.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Membrane Transporter/Ion Channel
Target Na+/K+ ATPase
Research Area Cardiovascular Disease
Indications Essential Hypertension

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Rostafuroxin sigma-tau i.f.r. S.p.A. Essential Hypertension 2006/12/21 Phase 2 Clinical
Rostafuroxin - Phase 2

Chemical Information

M.Wt Formula CAS No. Synonyms
374.51 C23H34O4 156722-18-8 PST-2238;PST 2238;PST2238; (3S,5R,8R,9S,10S,13S,14S,17S)-17-(furan-3-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol

Structure Information of Rostafuroxin

Smiles O[[email protected]]([[email protected]@](CC[[email protected]@]1([H])[[email protected]@]2(CC[[email protected]](O)C1)C)([H])[[email protected]]2([H])CC3)(CC[[email protected]@]4(C5=COC=C5)O)[[email protected]]34C
InChI InChI=1S/C23H34O4/c1-20-8-5-17(24)13-15(20)3-4-19-18(20)6-9-21(2)22(25,10-11-23(19,21)26)16-7-12-27-14-16/h7,12,14-15,17-19,24-26H,3-6,8-11,13H2,1-2H3/t15-,17+,18+,19-,20+,21-,22+,23+/m1/s1

Related Products

Other Form Products of Rostafuroxin

Name CAS Formula Suppliers

Recommended Products in Same Target

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Ouabain (Octahydrate) 11018-89-6 C29H60O20 3

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Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:DMSO:37.45mg/mL;100mM;ethanol:37.45mg/mL;100mM;
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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