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MLN1117

(CAS: 1268454-23-4)

Suppliers of MLN1117

Company Name Email Tel Country
BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: 98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD108/5mg () USD144/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Price and Availability: USD25/1mg () USD113/5mg () USD200/10mg () USD438/25mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD108/5mg () USD144/10mg ()
Quality Control & MSDS Files: LCMS HNMR HNMR LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Price and Availability: USD120/10mg () USD190/25mg () USD350/50mg () USD550/100mg () USD950/200mg () USD1850/500mg () USD2950/1g () USD3950/2g ()

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD108/5mg () USD144/10mg ()

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Background Information of MLN1117

MLN1117 is a selective p110α inhibitor with an IC50 of 15 nM.

Solubility of MLN1117

Solubility Sources
DMSO: > 6.4 mg/mL CHEMSCENE, LLC
DMSO: > 6.4 mg/mL MedChemexpress Co., Ltd.

Storage Condition of MLN1117

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
MLN1117 Millennium Pharmaceuticals, Inc. Endometrial Neoplasms 2016/3/28 2016/5/01 Phase 2 Clinical
MLN1117 Millennium Pharmaceuticals, Inc. Neoplasms, Advanced or Metastatic 2015/9/02 2016/3/01 Phase 1 Clinical
MLN1117 Millennium Pharmaceuticals, Inc. Metastatic Solid Tumors 2011/8/11 2015/12/01 Phase 1 Clinical
MLN1117 Millennium Pharmaceuticals, Inc. Non-small Cell Lung Cancer 2015/3/15 2016/5/01 Phase 2 Clinical
MLN1117 Millennium Pharmaceuticals, Inc. Clear-cell Metastatic Renal Cell Carcinoma 2016/3/25 2016/3/01 Phase 2 Clinical
MLN1117 - Phase 2

Chemical Information

M.Wt Formula CAS No. Synonyms
363.37 C19H17N5O3 1268454-23-4 Serabelisib;INK1117

Structure Information of MLN1117

Smiles O=C(C1=CN=C2C=CC(C3=CC=C(OC(N)=N4)C4=C3)=CN21)N5CCOCC5
InChI InChI=1S/C19H17N5O3/c20-19-22-14-9-12(1-3-16(14)27-19)13-2-4-17-21-10-15(24(17)11-13)18(25)23-5-7-26-8-6-23/h1-4,9-11H,5-8H2,(H2,20,22)

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Chemical and Physical Properties

Appearance:White to gray Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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