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(CAS: 66-22-8)

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Background Information of 2,4(1H,3H)-Pyrimidinedione

Uracil is one of the four nucleobases in the nucleic acid of RNA that are represented by the letters A, G, C and U. The others are adenine (A), cytosine (C), and guanine (G). In RNA, uracil binds to adenine via two hydrogen bonds. In DNA, the uracil nucleobase is replaced by thymine. Uracil is a demethylated form of thymine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for reactions in the human body and in plants. Uracil can be used to determine microbial contamination of tomatoes.

Solubility of 2,4(1H,3H)-Pyrimidinedione

Solubility Sources

Storage Condition of 2,4(1H,3H)-Pyrimidinedione

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways
Research Area

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
2,4(1H,3H)-Pyrimidinedione - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
112.09 C4H4N2O2 66-22-8 2,4(1H,3H)-Pyrimidinedione; 2,4-Dihydroxypyrimidine; pyrimidine-2,4(1H,3H)-dione

Structure Information of 2,4(1H,3H)-Pyrimidinedione

Smiles O=C(C=CN1)NC1=O
InChI InChI=1S/C4H4N2O2/c7-3-1-2-5-4(8)6-3/h1-2H,(H2,5,6,7,8)

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Safety Data of 2,4(1H,3H)-Pyrimidinedione

Hazard Symbols:Xi Risk Statements: Safety Statements:S24/25
Transport Information: HS Code: RTECS:YQ8650000
WGK Germany:2

Chemical and Physical Properties

Appearance: Melting point:>300 °C(lit.)
Boiling point: Flash Point:
Water Solubility: SOLUBLE IN HOT WATER Solubility:In vitro:DMSO,22 mg/mL(196.27 mM);In vitro:Ethanol,22 mg/mL(196.27 mM);In vitro:Water,Insoluble;In vivo:Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):5% DMSO+corn oilFor best results, use promptly a
Density: Merck:14,9850
BRN:606623 Refractive Index:
Vapour: EINECS:200-621-9
Optical Rotation: alpha:


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