• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

Defactinib

(CAS: 1073154-85-4)

Suppliers of Defactinib

Company Name Email Tel Country
AOBIOUS INC [email protected] (508) 306-0937 USA

Fax: Purity: Brand: AOBIOUS INC

Price and Availability: USD17/1mg ()

Active Biochem [email protected]; [email protected] 1-800-857-0985 (USA Toll Free#) USA

Fax: 1-201-884-1288 (USA Fax#)Purity: Brand:

Price and Availability: USD110/10mg ()

AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Price and Availability: USD320/5mg ()

Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Price and Availability: USD105/5mg (In stock)

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

BioVision, Inc., [email protected] 408-493-1800 Toll Free: 800-891-9699 (US Only) USA

Fax: 408-493-1801Purity: Brand:

Price and Availability: USD175/5mg ()

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 98% Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD84/5mg () USD108/10mg ()

Cayman Chemical Company [email protected] Toll Free (USA and Canada Only): (800) 364-9897; Direct: (734) 971-3335;Technical Support Toll Free (USA and Canada Only): (888) 526-5351;Technical Support Direct: (734) 975-3888 USA

Fax: (734) 971-3640Purity: Brand:

Price and Availability: USD29/1mg ()

ChemieTek [email protected] +1 (317) 598-0828 USA

Fax: +1 (317) 598-0835Purity: Brand:

Price and Availability: USD120/10mg () USD700/200mg ()

DC Chemicals [email protected]; [email protected] +86-21-58447131 China

Fax: +86-21-61642470Purity: Brand:

Price and Availability: USD400/100mg (In stock)

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD84/5mg () USD108/10mg ()
Quality Control & MSDS Files: HNMR LCMS HNMR HNMR HNMR HNMR LCMS LCMS MSDS

MedKoo Biosciences, Inc. [email protected] 919-279-0682 USA

Fax: 919-980-4831Purity: Brand:

Price and Availability: USD120/10mg ()

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: >98% Brand: Selleck

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD84/5mg () USD108/10mg ()

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD101/5mg () USD198/10mg () USD356/25mg () USD546/50mg () USD899/100mg ()

Inquiry Online

Salutation: *Country:
*Customer: *Company Name:
*Email: *Request quantity:
Remarks:
 

Notice: Your contact information will be sent to selected suppliers.

* Required Fields.

Background Information of Defactinib

Defactinib is a novel FAK inhibitor, which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.

Solubility of Defactinib

Solubility Sources
DMSO 50 mg/ml CHEMSCENE, LLC
DMSO 50 mg/ml MedChemexpress Co., Ltd.

Storage Condition of Defactinib

Storage Condition Sources
4°C MedChemexpress Co., Ltd.

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[HNMR] [LCMS] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Protein Tyrosine Kinase/RTK
Target FAK
Research Area Cancer
Indications Non Hematologic Cancers

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Defactinib Verastem, Inc. Non Hematologic Cancers 2013/9/11 Phase 1 Clinical
Defactinib - Phase 2

Chemical Information

M.Wt Formula CAS No. Synonyms
510.49 C20H21F3N8O3S 1073154-85-4 VS-6063;VS6063;VS 6063; N-methyl-4-((4-(((3-(N-methylmethylsulfonamido)pyrazin-2-yl)methyl)amino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)benzamide

Structure Information of Defactinib

Smiles O=C(NC)C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=NC=CN=C3N(C)S(=O)(C)=O)=N2)C=C1
InChI InChI=1S/C20H21F3N8O3S/c1-24-18(32)12-4-6-13(7-5-12)29-19-28-10-14(20(21,22)23)16(30-19)27-11-15-17(26-9-8-25-15)31(2)35(3,33)34/h4-10H,11H2,1-3H3,(H,24,32)(H2,27,28,29,30)

Related Products

Other Form Products of Defactinib

Name CAS Formula Suppliers
Defactinib (hydrochloride) 1073160-26-5 C20H22ClF3N8O3S 5

Recommended Products in Same Target

Name CAS Formula Suppliers
CEP-37440 1391712-60-9 C30H38ClN7O3 9
PND-1186 1061353-68-1 C25H26F3N5O3 13
PF-573228 869288-64-2 C22H20F3N5O3S 8
PF-562271 (besylate) 939791-38-5 C27H26F3N7O6S2 7
NVP-TAE 226 761437-28-9 C23H25ClN6O3 8
PF-431396 717906-29-1 C22H21F3N6O3S 5
PF-562271 717907-75-0 C21H20F3N7O3S 9
Y15 4506-66-5 C6H14Cl4N4 15
NAMI-A 201653-76-1 C8H16Cl4N4ORuS 4
Defactinib (hydrochloride) 1073160-26-5 C20H22ClF3N8O3S 5
GSK2256098 1224887-10-8 C20H23ClN6O2 5

Recommended Products in the Same Indication

Name CAS Formula Suppliers

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

Tags: buy Defactinib | Defactinib IC50 | Defactinib price | Defactinib cost | Defactinib solubility | Defactinib purchase | Defactinib manufacturer | Defactinib research buy | Defactinib order | Defactinib MSDS | Defactinib chemical structure | Defactinib Storage condition | Defactinib molecular weight | Defactinib mw | Defactinib datasheet | Defactinib supplier | Defactinib cell line | Defactinib NMR | Defactinib MS | Defactinib IR | Defactinib solubility | Defactinib Safe information | Defactinib Qc and Spectral Information | Defactinib Clinical Information | Defactinib Clinical Trial | Defactinib Route of Synthesis | Defactinib storage condition | Defactinib diseases and conditions | Defactinib flash point | Defactinib boiling point | Defactinib melting point | Defactinib storage condition | Defactinib brand