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4SC-202 (free base)

(CAS: 910462-43-0)

Suppliers of 4SC-202 (free base)

Company Name Email Tel Country
AbMole BioScience [email protected] 1-800-660-8580 USA

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AdooQ BioScience, LLC [email protected] 855-GO-ADOOQ (855-462-3667) (US & Canada Toll Free) 866-930-6790 (US & Canada Toll Free) +1-323-389-9269 (Outside of US & Canada) USA

Fax: 866-333-9607 (US & Canada Toll Free) +1-323-606-8156 (Outside of US & Canada)Purity: Brand:

Price and Availability: USD120/10mg ()

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

CHEMSCENE, LLC [email protected] 732-484-9848 USA

Fax: 888-484-5008Purity: Brand:

Price and Availability: USD120/5mg () USD180/10mg ()

MedChemexpress Co., Ltd. [email protected] 609-228-6898 USA

Fax: 609-228-5909Purity: Brand:

Price and Availability: USD120/5mg () USD180/10mg ()
Quality Control & MSDS Files: LCMS HNMR MSDS

Selleck Chemicals LLC [email protected] +1-832-582-8158 USA

Fax: +1-832-582-8590Purity: Brand:

Price and Availability: USD185/5mg (In stock)

Shanghai Haoyuan Chemexpress Co., Ltd. [email protected] +86 (21) 5187-0955 / +86 (21) 5895-5995 China

Fax: +86 (21) 5895-5996Purity: Brand:

Price and Availability: USD120/5mg () USD180/10mg ()

Shanghai XingMo Biotechnology Co., Ltd. [email protected] 13524779951 CHINA

Fax: Purity: > 98% Brand: X-MoBio

Price and Availability: USD1000/1g (In stock)

Target Molecule Corp. [email protected] (857) 239-0968 USA

Fax: 857-239-8801Purity: .98 Brand: TargetMol

Price and Availability: USD97/5mg () USD325/25mg () USD588/100mg ()

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Background Information of 4SC-202 (free base)

4SC-202 free base is an orally available potent HDACi specific for class I HDAC isoenzymes(NO HDAC8) with IC50s of 1.2/1.12/0.57 uM for HDAC1/2/3; high selectivity over ClassIIa/IIb/III HDACs. IC50 value: Target: HDAC1/2/3 The novel HDACi 4SC-202 is an orally available potent HDACi specific for class I HDAC isoenzymes.

Solubility of 4SC-202 (free base)

Solubility Sources
DMSO MedChemexpress Co., Ltd.

Storage Condition of 4SC-202 (free base)

Storage Condition Sources

MSDS Information

MSDS Sources
MedChemexpress Co., Ltd.

Quality Control and Spectral Data

QC Reports Sources
[LCMS] [HNMR] MedChemexpress Co., Ltd.

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage Epigenetics
Target HDAC
Research Area Cancer
Indications Advanced Hematologic Malignancies

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
4SC-202 (free base) 4SC AG Advanced Hematologic Malignancies 2011/4/12 Phase 1 Clinical
4SC-202 (free base) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
447.51 C23H21N5O3S 910462-43-0 4SC 202 free base;4SC202 free base; (E)-N-(2-aminophenyl)-3-(1-((4-(1-methyl-1H-pyrazol-4-yl)phenyl)sulfonyl)-1H-pyrrol-3-yl)acrylamide

Structure Information of 4SC-202 (free base)

Smiles O=C(NC1=CC=CC=C1N)/C=C/C2=CN(S(=O)(C3=CC=C(C4=CN(C)N=C4)C=C3)=O)C=C2
InChI InChI=1S/C23H21N5O3S/c1-27-16-19(14-25-27)18-7-9-20(10-8-18)32(30,31)28-13-12-17(15-28)6-11-23(29)26-22-5-3-2-4-21(22)24/h2-16H,24H2,1H3,(H,26,29)/b11-6+

Related Products

Other Form Products of 4SC-202 (free base)

Name CAS Formula Suppliers
4SC-202 1186222-89-8 C30H29N5O6S2 13

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Recommended Products in the Same Indication

Name CAS Formula Suppliers
4SC-202 1186222-89-8 C30H29N5O6S2 13

Chemical and Physical Properties

Appearance:White to off-white Solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:In vitro:DMSO,89 mg/mL(198.87 mM);In vitro:Water,Insoluble;In vitro:Ethanol,Insoluble;In vivo:Add solvents to the product individually and in order(Data is from Selleck tests instead of citations):2% DMSO+30% PEG 300+5% Tween 80+ddH2OFor best results, use
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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