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MMAD (hydrochloride)

(CAS: 173441-26-4)

Suppliers of MMAD (hydrochloride)

Company Name Email Tel Country
Apexbio Technology LLC [email protected] +1-832-696-8203 USA

Fax: +1-832-641-3177Purity: Brand:

Ark Pharm, Inc. [email protected] +1 (847) 367-3680 USA

Fax: +1 (847) 367-3681Purity: Brand:

BOC Sciences [email protected] 1-631-504-6093

Fax: 1-631-614-7828Purity: >98% Brand: BOC Sciences

Biochempartner Co., Ltd [email protected] 0086-13720134139; 0086-15971444841 China

Fax: Purity: 0.98 Brand: Biochempartner

ProbeChem [email protected] 86-21-80183644

Fax: 86-21-68860190Purity: Brand:

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Background Information of MMAD (hydrochloride)

A potent tubulin inhibitor that is a toxin payload in antibody drug conjugates (ADCs).

Solubility of MMAD (hydrochloride)

Solubility Sources

Storage Condition of MMAD (hydrochloride)

Storage Condition Sources

MSDS Information

MSDS Sources

Quality Control and Spectral Data

QC Reports Sources

Mechanism and Indications

Signaling Pathways Cell Cycle/DNA Damage Cytoskeleton Antibody-drug Conjugate/ADC Related
Target Microtubule/Tubulin ADC Cytotoxin
Research Area Cancer

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
MMAD (hydrochloride) - Not Found
MMAD (hydrochloride) - No Development Reported

Chemical Information

M.Wt Formula CAS No. Synonyms
807.5253 C41H67ClN6O6S 173441-26-4 Demethyldolastatin 10 hydrochloride;Monomethylauristatin D hydrochloride;Monomethyl Dolastatin 10 hydrochloride

Structure Information of MMAD (hydrochloride)

Smiles O=C([[email protected]](C)[[email protected]]([[email protected]]1([H])CCCN1C(C[[email protected]@H](OC)[[email protected]]([[email protected]@H](C)CC)N(C([[email protected]@H](NC([[email protected]@H](N(C)[H])C(C)C)=O)C(C)C)=O)C)=O)OC)N[[email protected]@H](CC2=CC=CC=C2)C3=NC=CS3.Cl
InChI InChI=1S/C41H66N6O6S.ClH/c1-12-27(6)36(46(9)41(51)35(26(4)5)45-39(50)34(42-8)25(2)3)32(52-10)24-33(48)47-21-16-19-31(47)37(53-11)28(7)38(49)44-30(40-43-20-22-54-40)23-29-17-14-13-15-18-29;/h13-15,17-18,20,22,25-28,30-32,34-37,42H,12,16,19,21,23-24H2,1-11H3,(H,44,49)(H,45,50);1H/t27-,28+,30-,31-,32+,34-,35-,36-,37+;/m0./s1

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Chemical and Physical Properties

Appearance:White to off-white solid Melting point:
Boiling point: Flash Point:
Water Solubility: Solubility:10 mM in DMSO
Density: Merck:
BRN: Refractive Index:
Vapour: EINECS:
Optical Rotation: alpha:

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