• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

(PF-06767832)

1

Identification

PF-06767832 PF-06767832
Name PF-06767832
Formula C22H23N3O3S
MW 409.5
CAS No.
EINECS
Smiles C1(C(N[[email protected]]2CCOC[[email protected]@H]2O)=O)=NC=C(C)C(CC2=CC=C(C3=CSC=N3)C=C2)=C1 |&1:3,8,r|
Synonyms
InChI InChI=1/C22H23N3O3S/c1-14-10-23-19(22(27)25-18-6-7-28-11-21(18)26)9-17(14)8-15-2-4-16(5-3-15)20-12-29-13-24-20/h2-5,9-10,12-13,18,21,26H,6-8,11H2,1H3,(H,25,27)/t18-,21-/s3
2

Introduction

PF-06767832 is a selective M1 muscarinic acetylcholine receptor (mAChR) positive allosteric modulator (PAM) has been increasingly explored as a potential approach for the treatment of Alzheimer’s disease (AD) and other cognitive deficit disorders.

Background Information

3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance: EBNumber:EB100692496

Storage condition

Solubility

5

Mechanism and Indication

Signaling Pathways Neuronal Signaling GPCR/G Protein
Target mAChR
Research Area Neurological Disease
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
7

Safety Data of PF-06767832

8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AMEDCHEM CHINA
10

Related Products

Other Forms of

Name CAS No Formula MW

Recommended Compounds in mAChR

Name CAS No Formula MW
Pilocarpine (Hydrochloride) 54-71-7 C11H17ClN2O2 244.72
Imidafenacin 170105-16-5 C20H21N3O 319.4
Flavoxate (hydrochloride) 3717-88-2 C24H26ClNO4 427.92
Homatropine (Bromide) 51-56-9 C16H22BrNO3 356.25
Benztropine (mesylate) 132-17-2 C22H29NO4S 403.54
Otilonium (bromide) 26095-59-0 C29H43BrN2O4 563.57
Arecoline (hydrobromide) 300-08-3 C8H14BrNO2 236.11
Trospium (chloride) 10405-02-4 C25H30ClNO3 427.96
Tiotropium (bromide hydrate) 139404-48-1 C19H24BrNO5S2 490.43
Revefenacin 864750-70-9 C35H43N5O4 597.747
Oxybutynin (chloride) 1508-65-2 C22H32ClNO3 393.95
Gallamine Triethiodide 65-29-2 C30H60I3N3O3 891.53
Bethanechol (chloride) 590-63-6 C7H17ClN2O2 196.68
Atropine (sulfate monohydrate) 5908-99-6 C34H50N2O11S 694.83
Methscopolamine (bromide) 155-41-9 C18H24BrNO4 398.29
Irsogladine (maleate) 84504-69-8 C13H11Cl2N5O4 372.16
Irsogladine 57381-26-7 C9H7Cl2N5 256.09
Tropicamide 1508-75-4 C17H20N2O2 284.35
Oxybutynin 5633-20-5 C22H31NO3 357.49
Ipratropium (bromide) 22254-24-6 C20H30BrNO3 412.36

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

PF-06767832

Tags: buy PF-06767832 IC50 | PF-06767832 price | PF-06767832 cost | PF-06767832 solubility | PF-06767832 purchase | PF-06767832 manufacturer | PF-06767832 research buy | PF-06767832 order | PF-06767832 MSDS | PF-06767832 chemical structure | PF-06767832 Storage condition | PF-06767832 molecular weight | PF-06767832 mw | PF-06767832 datasheet | PF-06767832 supplier | PF-06767832 cell line | PF-06767832 NMR | PF-06767832 MS | PF-06767832 IR | PF-06767832 solubility | PF-06767832 Safe information | PF-06767832 Qc and Spectral Information | PF-06767832 Clinical Information | PF-06767832 Clinical Trial | PF-06767832 Route of Synthesis | PF-06767832 storage condition | PF-06767832 diseases and conditions | PF-06767832 flash point | PF-06767832 boiling point | PF-06767832 melting point | PF-06767832 storage condition | PF-06767832 brand