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2222643-58-3 (RG-06)

1

Identification

RG-06 RG-06
Name RG-06
Formula C24H23NO4S
MW 421.51
CAS No. 2222643-58-3
EINECS
Smiles [[email protected]]12(CCCC(=O)[[email protected]@]1([H])CC1(S(=O)(=O)C3C=CC(C)=CC=3)C(=O)C3N2C1C1C=CC=CC=13)[H] |&1:0,6|
Synonyms
InChI InChI=1S/C24H23NO4S/c1-14-9-11-15(12-10-14)30(28,29)24-13-18-19(7-4-8-20(18)26)25-21(23(24)27)16-5-2-3-6-17(16)22(24)25/h2-3,5-6,9-12,18-19,21-22H,4,7-8,13H2,1H3/t18-,19+,21?,22?,24?/m0/s1
2

Introduction

RG-06 is a M3-muscarinic acetylcholine receptor (mAChR) antagonist with a pIC50 of 9.890±0.182.

Background Information

3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance: EBNumber:EB100145226

Storage condition

Solubility

5

Mechanism and Indication

Signaling Pathways Neuronal Signaling GPCR/G Protein
Target mAChR
Research Area Neurological Disease
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
7

Safety Data of RG-06

8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AMEDCHEM CHINA
10

Related Products

Other Forms of 2222643-58-3

Name CAS No Formula MW

Recommended Compounds in mAChR

Name CAS No Formula MW
Pilocarpine (Hydrochloride) 54-71-7 C11H17ClN2O2 244.72
Imidafenacin 170105-16-5 C20H21N3O 319.4
Flavoxate (hydrochloride) 3717-88-2 C24H26ClNO4 427.92
Homatropine (Bromide) 51-56-9 C16H22BrNO3 356.25
Benztropine (mesylate) 132-17-2 C22H29NO4S 403.54
Otilonium (bromide) 26095-59-0 C29H43BrN2O4 563.57
Arecoline (hydrobromide) 300-08-3 C8H14BrNO2 236.11
Trospium (chloride) 10405-02-4 C25H30ClNO3 427.96
Tiotropium (bromide hydrate) 139404-48-1 C19H24BrNO5S2 490.43
Revefenacin 864750-70-9 C35H43N5O4 597.747
Oxybutynin (chloride) 1508-65-2 C22H32ClNO3 393.95
Gallamine Triethiodide 65-29-2 C30H60I3N3O3 891.53
Bethanechol (chloride) 590-63-6 C7H17ClN2O2 196.68
Atropine (sulfate monohydrate) 5908-99-6 C34H50N2O11S 694.83
Methscopolamine (bromide) 155-41-9 C18H24BrNO4 398.29
Irsogladine (maleate) 84504-69-8 C13H11Cl2N5O4 372.16
Irsogladine 57381-26-7 C9H7Cl2N5 256.09
Tropicamide 1508-75-4 C17H20N2O2 284.35
Oxybutynin 5633-20-5 C22H31NO3 357.49
Ipratropium (bromide) 22254-24-6 C20H30BrNO3 412.36

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

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References

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More Information

RG-06

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