• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

148396-36-5 (Fradafiban)

1

Identification

Fradafiban Fradafiban
Name Fradafiban
Formula C20H21N3O4
MW 367.4
CAS No. 148396-36-5
EINECS
Smiles O=C(O)C[[email protected]]1C(N[[email protected]](COC2=CC=C(C3=CC=C(C(N)=N)C=C3)C=C2)C1)=O
Synonyms BIBU52;BIBU-52;BIBU 52; 2-((3S,5S)-5-(((4'-carbamimidoyl-[1,1'-biphenyl]-4-yl)oxy)methyl)-2-oxopyrrolidin-3-yl)acetic acid
InChI InChI=1S/C20H21N3O4/c21-19(22)14-3-1-12(2-4-14)13-5-7-17(8-6-13)27-11-16-9-15(10-18(24)25)20(26)23-16/h1-8,15-16H,9-11H2,(H3,21,22)(H,23,26)(H,24,25)/t15-,16-/m0/s1
2

Introduction

Fradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.

Background Information

Fradafiban is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. ......by MedChemexpress Co., Ltd.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance: EBNumber:EB000129507

Storage condition

Solubility

5

Mechanism and Indication

Signaling Pathways Others
Target Others
Research Area
Indications Healthy Healthy Healthy
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Fradafiban Boehringer Ingelheim Healthy 1999/1/1 Phase 1
Fradafiban Boehringer Ingelheim Healthy 1998/4/1 Phase 1
Fradafiban Boehringer Ingelheim Healthy 1998/4/1 Phase 1
7

Safety Data of Fradafiban

8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
CHEMSCENE, LLC 1mg/USD1644();5mg/USD3288() USA
MedChemexpress Co., Ltd. 1mg/USD1644();5mg/USD3288() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 1mg/USD1644();5mg/USD3288() China
10

Related Products

Other Forms of 148396-36-5

Name CAS No Formula MW

Recommended Compounds in Others

Name CAS No Formula MW
(R)-(+)-Etomoxir (sodium salt) 828934-41-4 C15H18ClNaO4 320.74
Dictamine 484-29-7 C12H9NO2 199.21
3,3',5-Triiodo-L-thyronine (sodium) 55-06-1 C15H11I3NNaO4 672.9553
Fabomotizole (hydrochloride) 173352-39-1 C15H22ClN3O2S 343.8721
FPH2 957485-64-2 C14H16ClN5O2S 353.83
α-Tocopherol (phosphate) 38976-17-9 C29H51O5P 510.69
BAMB-4 891025-25-5 C15H12N2O2 252.27
LDN-27219 312946-37-5 C20H16N4O2S2 408.5
ISO-1 478336-92-4 C12H13NO4 235.24
Aurothioglucose 12192-57-3 C6H11AuO5S 392.18
Oxybenzone 131-57-7 C14H12O3 228.24
ITX3 347323-96-0 C22H17N3OS 371.45
Cardiogreen 3599-32-4 C43H47N2NaO6S2 774.96
Skp2 Inhibitor C1 432001-69-9 C18H13BrN2O4S2 465.34
INH1 313553-47-8 C18H16N2OS 308.4
PF6-AM 1268491-69-5 C33H31BO12 630.4
XEN445 1515856-92-4 C18H17F3N2O3 366.33
Disperse Blue 148 52239-04-0 C19H19N5O4S 413.45026
Solvent Blue 35 17354-14-2 C22H26N2O2 350.454
CID-797718 370586-05-3 C12H11NO3 217.2206

Recommended Compounds in Same Indication

Name CAS No Formula MW
VGX-1027 6501-72-0 C11H11NO3 205.21
AZD1981 802904-66-1 C19H17ClN2O3S 388.87
4-Thiazolidinone, 5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]methylene]-3-(2-methylphenyl)-2-(propylimino)-, (2Z,5Z)- 854107-55-4 C22H23ClN2O4S 446.95
RSV604 676128-63-5 C22H17FN4O2 388.39
Cilobradine (hydrochloride) 186097-54-1 C28H39ClN2O5 519.07
Vipadenant 442908-10-3 C16H15N7O 321.3366
Cilobradine 147541-45-5 C28H38N2O5 482.61
PF-04418948 1078166-57-0 C23H20FNO5 409.41
JNJ-40411813 1127498-03-6 C20H25ClN2O 344.88
GLPG0634 1206161-97-8 C21H23N5O3S 425.504
GLPG0492 1215085-92-9 C19H14F3N3O3 389.328
BI 224436 1155419-89-8 C27H26N2O4 442.51
Heparin 9005-49-6 C26H42N2O37S5 1134.93
Vadadustat 1000025-07-9 C14H11ClN2O4 0.0
MGB-BP-3 1000277-08-6 C36H37N7O4 631.72
VITAMIN K1 12001-79-5 C31H46O2 450.7
Tenapanor 1234423-95-0 C50H66Cl4N8O10S2 1145.05
GLPG0187 1320346-97-1 C29H37N7O5S 595.71
Iberdomide 1323403-33-3 C25H27N3O5 449.49898
Terbogrel 149979-74-8 C23H27N5O2 405.49
11

Route of Synthesis

12

References

Protocol Reference

13

More Information

Fradafiban

Tags: buy 148396-36-5 IC50 | 148396-36-5 price | 148396-36-5 cost | 148396-36-5 solubility | 148396-36-5 purchase | 148396-36-5 manufacturer | 148396-36-5 research buy | 148396-36-5 order | 148396-36-5 MSDS | 148396-36-5 chemical structure | 148396-36-5 Storage condition | 148396-36-5 molecular weight | 148396-36-5 mw | 148396-36-5 datasheet | 148396-36-5 supplier | 148396-36-5 cell line | 148396-36-5 NMR | 148396-36-5 MS | 148396-36-5 IR | 148396-36-5 solubility | 148396-36-5 Safe information | 148396-36-5 Qc and Spectral Information | 148396-36-5 Clinical Information | 148396-36-5 Clinical Trial | 148396-36-5 Route of Synthesis | 148396-36-5 storage condition | 148396-36-5 diseases and conditions | 148396-36-5 flash point | 148396-36-5 boiling point | 148396-36-5 melting point | 148396-36-5 storage condition | 148396-36-5 brand