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55-48-1 (Atropine sulfate)

1

Identification

Atropine sulfate Atropine sulfate
Name Atropine sulfate
Formula C34H48N2O10S
MW 676.82
CAS No. 55-48-1
EINECS 200-235-0
Smiles O=C(C(CO)C1=CC=CC=C1)O[[email protected]]2C[[email protected]](CC3)([H])N(C)[[email protected]]3([H])C2.O=C(C(CO)C4=CC=CC=C4)O[[email protected]]5C[[email protected]](CC6)([H])N(C)[[email protected]]6([H])C5.OS(O)(=O)=O
Synonyms (8-Methyl-8-azabicyclo[3.2.1]oct-3-yl) 3-hydroxy-2-phenyl-propanoate sulphate; (1R,3r,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl 3-hydroxy-2-phenylpropanoate hemisulfate
InChI InChI=1S/2C17H23NO3.H2O4S/c2*1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12;1-5(2,3)4/h2*2-6,13-16,19H,7-11H2,1H3;(H2,1,2,3,4)/t2*13-,14+,15+,16?;
2

Introduction

Competitive antagonist of the muscarinic acetylcholine receptors

Background Information

Competitive antagonist of the muscarinic acetylcholine receptors ......by AOBIOUS INC
Atropine sulfate is a competitive nonselective antagonist at central and peripheral muscarinic acetylcholine receptors. This medication is used before eye examinations and to treat certain eye conditions. It belongs to a class of drugs known as anticholinergics. ......by MedKoo Biosciences, Inc.
Atropine is an antimuscarinic agent and has shown the pharmacological effects because of binding to muscarinic acetylcholine receptors. Atropine, the orthosteric antagonist, has been reported to compete with [3H]-NMS for all muscarinic subtypes with a potency consistent with the high affinities at the mAChR subtypes ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance: EBNumber:EB000029261

Storage condition

Solubility

10 mM in H2O (free soluble) by CHEMSCENE, LLC
10 mM in H2O (free soluble) by MedChemexpress Co., Ltd.
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Mechanism and Indication

Signaling Pathways Neuronal Signaling GPCR/G Protein
Target mAChR
Research Area Neurological Disease
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Atropine sulfate - Launched
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Safety Data of Atropine sulfate

´╗┐Hazard Symbols : T+
´╗┐Risk Statements : 26/28
Safety Statements : 23-45
WGKGermany : 2
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Spectral Information

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Suppliers List

Company Price and Availability Country/Region
AOBIOUS INC USA
Ark Pharm, Inc. USA
Avonchem/Chromos Express Ltd.
BOC Sciences
Biochempartner Co., Ltd China
CHEMSCENE, LLC 100mg/USD60() USA
MedChemexpress Co., Ltd. 100mg/USD60() USA
MedKoo Biosciences, Inc. USA
Santa Cruz Biotechnology, Inc. 1g/USD560() USA
Selleck Chemicals LLC USA
Shanghai Everchem Co., Ltd. China
Shanghai Haoyuan Chemexpress Co., Ltd. 100mg/USD60() China
Shanghai Pharmarketech Co., Ltd. China
Target Molecule Corp. 5mg/USD24();10mg/USD45();25mg/USD80();50mg/USD133();200mg/USD244() USA
Xiangyang Jinsheng Pharmaceutical Co., Ltd. China
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Related Products

Other Forms of 55-48-1

Name CAS No Formula MW
Atropine (sulfate monohydrate) 5908-99-6 C34H50N2O11S 694.83
Atropine 51-55-8 C17H23NO3 289.37

Recommended Compounds in mAChR

Name CAS No Formula MW
Pilocarpine (Hydrochloride) 54-71-7 C11H17ClN2O2 244.72
Imidafenacin 170105-16-5 C20H21N3O 319.4
Flavoxate (hydrochloride) 3717-88-2 C24H26ClNO4 427.92
Homatropine (Bromide) 51-56-9 C16H22BrNO3 356.25
Benztropine (mesylate) 132-17-2 C22H29NO4S 403.54
Otilonium (bromide) 26095-59-0 C29H43BrN2O4 563.57
Arecoline (hydrobromide) 300-08-3 C8H14BrNO2 236.11
Trospium (chloride) 10405-02-4 C25H30ClNO3 427.96
Tiotropium (bromide hydrate) 139404-48-1 C19H24BrNO5S2 490.43
Revefenacin 864750-70-9 C35H43N5O4 597.747
Oxybutynin (chloride) 1508-65-2 C22H32ClNO3 393.95
Gallamine Triethiodide 65-29-2 C30H60I3N3O3 891.53
Bethanechol (chloride) 590-63-6 C7H17ClN2O2 196.68
Atropine (sulfate monohydrate) 5908-99-6 C34H50N2O11S 694.83
Methscopolamine (bromide) 155-41-9 C18H24BrNO4 398.29
Irsogladine (maleate) 84504-69-8 C13H11Cl2N5O4 372.16
Irsogladine 57381-26-7 C9H7Cl2N5 256.09
Tropicamide 1508-75-4 C17H20N2O2 284.35
Oxybutynin 5633-20-5 C22H31NO3 357.49
Ipratropium (bromide) 22254-24-6 C20H30BrNO3 412.36

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

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More Information

Atropine sulfate

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