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103-90-2 (Acetaminophen)

1

Identification

Acetaminophen Acetaminophen
Name Acetaminophen
Formula C8H9NO2
MW 151.16
CAS No. 103-90-2
EINECS 203-157-5
Smiles CC(NC1=CC=C(O)C=C1)=O
Synonyms p-Hydroxyacetanilide; Acetaminophen; Paracetamol; N-Acetyl-4-aminophenol; APAP; N-(4-hydroxyphenyl)acetamide
InChI InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)
2

Introduction

Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor. Target: COX-2 Acetaminophen acts functionally as a selective COX-2 inhibitor led us to investigate the hypothesis of whether it works via preferential COX-2 blockade.

Background Information

A selective COX-2 inhibitor ......by BOC Sciences
Acetaminophen (paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic drug. ......by MedChemexpress Co., Ltd.
Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000020213

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways Immunology/Inflammation
Target COX
Research Area Inflammation/Immunology
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Acetaminophen - Launched
7

Safety Data of Acetaminophen

Hazard Symbols : Xn
Risk Statements : R22;R36/38;R52/53
Safety Statements : S26;S37/39;S61
HS Code : 29242930
RTECS : AE4200000
WGKGermany : 1
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Aakash Chemicals and Dye-Stuffs, Inc. USA
Abcam 100mg/USD69() USA
Aladdin China
Alfa Chemistry USA
Anhui Modern Chem-Pharm Co., Ltd. China
BOC Sciences
CHEMSCENE, LLC 5g/USD60();10g/USD96() USA
Cayman Chemical Company 100g/USD19() USA
Changzhou Sunchem Pharmaceutical Chemical Material Co., Ltd. China
Clearsynth Labs Limited 25mg/USD100() India
Freedom Chemical Supply USA
Jinshi General Pharmaceutical Factory China
MedChemexpress Co., Ltd. 5g/USD60();10g/USD96() USA
SL Drugs and Pharmaceuticals Pvt. Ltd. India
Santa Cruz Biotechnology, Inc. 5g/USD20() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 5g/USD60();10g/USD96() China
Sigma-Aldrich, Inc. 100g/USD42() USA
Spectrum Chemical Mfg. Corp. 125g/USD64() USA
Taixing YangZi Pharm chemical Co., Ltd China
Taiyuan Pharmaceutical Works Co., Ltd. China
Target Molecule Corp. 5mg/USD20();10mg/USD40();50mg/USD78();100mg/USD125();200mg/USD183() USA
Tocris Bioscience Inc. 100mg/USD95() USA
Tokyo Chemical Industry Co., Ltd. 25g/USD16() Japan
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Related Products

Other Forms of 103-90-2

Name CAS No Formula MW
4-Acetamidophenyl acetate 2623-33-8 C10H11NO3 193.2

Recommended Compounds in COX

Name CAS No Formula MW
Isoorientin 4261-42-1 C21H20O11 448.3769
Maslinic acid 4373-41-5 C30H48O4 472.7
Aceclofenac 89796-99-6 C16H13Cl2NO4 354.18
Zaltoprofen 74711-43-6 C17H14O3S 298.36
Ketorolac 74103-06-3 C15H13NO3 255.27
Loxoprofen 68767-14-6 C15H18O3 246.3
Mefenamic acid 61-68-7 C15H15NO2 241.29
Nabumetone 42924-53-8 C15H16O2 228.29
Triflusal 322-79-2 C10H7F3O4 248.16
Diclofenac (diethylamine) 78213-16-8 C18H22Cl2N2O2 369.29
Bufexamac 2438-72-4 C12H17NO3 223.27
Acemetacin 53164-05-9 C21H18ClNO6 415.82
Phenacetin 62-44-2 C10H13NO2 179.22
Tenoxicam 59804-37-4 C13H11N3O4S2 337.37
Flunixin (meglumine) 42461-84-7 0.0
Lornoxicam 70374-39-9 C13H10ClN3O4S2 371.82
Nimesulide 51803-78-2 C13H12N2O5S 308.31
Tolfenamic Acid 13710-19-5 C14H12ClNO2 261.7
Fenoprofen (Calcium) 34597-40-5 C30H26CaO6 522.6
Deracoxib 169590-41-4 C17H14F3N3O3S 397.37

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

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More Information

Acetaminophen

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