• Search chemicals, activators, Inhibitors, APIs, intermediates and raw materials.

10236-47-2 (Naringin)

1

Identification

Naringin Naringin
Name Naringin
Formula C27H32O14
MW 580.53
CAS No. 10236-47-2
EINECS 233-566-4
Smiles O=C(C1)C(C(O)=C2)=C(C=C2O[[email protected]](O[[email protected]@H]3CO)[[email protected]@H]([[email protected]@H](O)[[email protected]@H]3O)O[[email protected]]4[[email protected]](O)[[email protected]](O)[[email protected]@H](O)[[email protected]](C)O4)O[[email protected]@H]1C5=CC=C(O)C=C5
Synonyms 7-(2-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyloxy)-2,3-dihydro-4',5,7-trihydroxyflavone; 7-[[2-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-5-hydroxy-2(S)-(4-hydroxyphe; (S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one
InChI InChI=1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1
2

Introduction

Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities.

Background Information

Naringin inhibits hepatic P-glycoprotein (P-gp) and some drug-metabolizing cytochrome P450 enzymes, including CYP3A4 and CYP1A2, which may result in drug-drug interactions. ......by BOC Sciences
Naringin is a major flavanone glycoside obtained from tomatoes, grapefruits, and many other citrus fruits. Naringin exhibits biological properties such as antioxidant, anti-inflammatory, and antiapoptotic activities. ......by MedChemexpress Co., Ltd.
Naringin is a flavanone glycoside, which exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of cytochrome P450 enzymes. ......by Selleck Chemicals LLC
Naringin is a flavanone glycoside, which exerts a variety of pharmacological effects such as antioxidant activity, blood lipid lowering, anticancer activity, and inhibition of cytochrome P450 enzymes. ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000015326

Storage condition

Solubility

DMSO:116 mg/mL (199.81 mM); Ethanol: 2 mg/mL (3.44 mM); Water: <1 mg/mL (<1 mM) by CHEMSCENE, LLC
DMSO:116 mg/mL (199.81 mM); Ethanol: 2 mg/mL (3.44 mM); Water: <1 mg/mL (<1 mM) by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 116 mg/mL (199.81 mM); Ethanol2 mg/mL (3.44 mM); Water<1 mg/mL (<1 mM) by Selleck Chemicals LLC
5

Mechanism and Indication

6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Naringin - No Development Reported
7

Safety Data of Naringin

Hazard Symbols : Xn,Xi
Risk Statements : 22-36/37/38
Safety Statements : S24/25
RTECS : QN6340000
WGKGermany : 3
8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Aladdin 10g/RMB89();50g/RMB365() China
BOC Sciences
Biochempartner Co., Ltd China
CHEMSCENE, LLC 200mg/USD60();10g/USD84() USA
Changsha Huakang Bio-Techology Development Co., Ltd. China
Hangzhou Lin'an Tianhong Bio-tech Co., Ltd. China
MedChemexpress Co., Ltd. 200mg/USD60();10g/USD84() USA
Santa Cruz Biotechnology, Inc. 25g/USD38();100g/USD92() USA
Selleck Chemicals LLC 500mg/USD50(In stock);10mM/1mLIn DMSO/USD420(In stock) USA
Shaanxi Jiahe Phytochem Co., Ltd. China
Shaanxi Sciphar Biotechnology Co., Ltd. China
Shanghai Haoyuan Chemexpress Co., Ltd. 200mg/USD60();10g/USD84() China
Shannxi Huike Botanical Development Co., Ltd. China
Shenzhen Winkey Bio-Tech Co., Ltd. China
Sigma-Aldrich, Inc. 25g/USD45();500mg/USD75();100g/USD158() USA
Sino-Future Bio-Tech Co., Ltd. China
Target Molecule Corp. 5mg/USD20();50mg/USD153();100mg/USD299() USA
Tocris Bioscience Inc. 25g/USD25();50g/USD48();100g/USD90();250g/USD200() USA
Tokyo Chemical Industry Co., Ltd. 25g/USD25() Japan
10

Related Products

Other Forms of 10236-47-2

Name CAS No Formula MW
Naringin Dihydrochalcone 18916-17-1 C27H36Cl2O14 655.47

Recommended Compounds in Autophagy Cytochrome P450

Name CAS No Formula MW
Pirarubicin (Hydrochloride) 95343-20-7 C32H38ClNO12 664.1
Berberine (chloride) 633-65-8 C20H18ClNO4 371.8142
DMH-1 1206711-16-1 C24H20N4O 380.44
CB-839 1439399-58-2 C26H24F3N7O3S 571.57
H-89 (dihydrochloride) 130964-39-5 C20H22BrCl2N3O2S 519.2826
Shikonin 517-89-5 C16H16O5 288.3
H 89 127243-85-0 C20H20BrN3O2S 446.36
Eupatilin 22368-21-4 C18H16O7 344.32
Isoalantolactone 470-17-7 C15H20O2 232.32
Scutellarein 529-53-3 C15H10O6 286.24
Leonurine 24697-74-3 C14H21N3O5 311.33
Berbamine (dihydrochloride) 6078-17-7 C37H42Cl2N2O6 681.6452
Ruxolitinib (S enantiomer) 941685-37-6 C17H18N6 306.37
D-Glucosamine (Hydrochloride) 66-84-2 C6H14ClNO5 215.63
Schizandrin A 61281-38-7 C22H28O6 388.45
Schisandrol B 58546-54-6 C23H28O7 416.46
Schisandrol A 7432-28-2 C24H32O7 432.51
Icaritin 118525-40-9 C21H20O6 368.3799
Bicyclol 118159-48-1 C19H18O9 390.34
Azithromycin 83905-01-5 C38H72N2O12 748.9845

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

13

More Information

Naringin

Tags: buy 10236-47-2 IC50 | 10236-47-2 price | 10236-47-2 cost | 10236-47-2 solubility | 10236-47-2 purchase | 10236-47-2 manufacturer | 10236-47-2 research buy | 10236-47-2 order | 10236-47-2 MSDS | 10236-47-2 chemical structure | 10236-47-2 Storage condition | 10236-47-2 molecular weight | 10236-47-2 mw | 10236-47-2 datasheet | 10236-47-2 supplier | 10236-47-2 cell line | 10236-47-2 NMR | 10236-47-2 MS | 10236-47-2 IR | 10236-47-2 solubility | 10236-47-2 Safe information | 10236-47-2 Qc and Spectral Information | 10236-47-2 Clinical Information | 10236-47-2 Clinical Trial | 10236-47-2 Route of Synthesis | 10236-47-2 storage condition | 10236-47-2 diseases and conditions | 10236-47-2 flash point | 10236-47-2 boiling point | 10236-47-2 melting point | 10236-47-2 storage condition | 10236-47-2 brand