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169590-41-4 (Deracoxib)

1

Identification

Deracoxib Deracoxib
Name Deracoxib
Formula C17H14F3N3O3S
MW 397.37
CAS No. 169590-41-4
EINECS
Smiles O=S(C(C=C1)=CC=C1N2N=C(C(F)F)C=C2C3=CC=C(OC)C(F)=C3)(N)=O
Synonyms Deram; Deramaxx; SC 046; SC 46; SC 59046; 4-[5-(3-Fluoro-4-methoxyphenyl)-3-(difluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide; 4-(3-(difluoromethyl)-5-(3-fluoro-4-methoxyphenyl)-1H-pyrazol-1-yl)benzenesulfonamide
InChI InChI=1S/C17H14F3N3O3S/c1-26-16-7-2-10(8-13(16)18)15-9-14(17(19)20)22-23(15)11-3-5-12(6-4-11)27(21,24)25/h2-9,17H,1H3,(H2,21,24,25)
2

Introduction

Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID).

Background Information

Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent and specific cyclooxygenase-2 (COX-2) inhibitor. Used in dogs to treat pain associated with osteoarthritis, or to prevent pain following orthopedic or dental surgery. ......by BioVision, Inc.,
Deracoxib is an NSAID and COX-2 inhibitor used to treat osteoarthritis. It induces cell cycle arrest and apoptosis in mammary tumor cells, decreases platelet aggregation, and lowers inflammatory responses. ......by MedKoo Biosciences, Inc.
A selective COX-2 inhibitor that is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). ......by ProbeChem
Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). ......by Target Molecule Corp.
3

Protocol(Only for Reference)

Cell Experiment

Animal Experiment

4

Physical and Chemical Properties

Appearance:Light yellow to yellow Solid EBNumber:EB000012616

Storage condition

Solubility

DMSO by MedChemexpress Co., Ltd.
5

Mechanism and Indication

Signaling Pathways Immunology/Inflammation
Target COX
Research Area Inflammation/Immunology
Indications
6

Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Deracoxib - No Development Reported
Deracoxib - Launched
7

Safety Data of Deracoxib

8

Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
Apexbio Technology LLC USA
Ark Pharm, Inc. 1g/USD2500() USA
Astatech, Inc. USA
BOC Sciences
BioVision, Inc., USA
Biochempartner Co., Ltd China
CHEMSCENE, LLC 100mg/USD144();500mg/USD600() USA
Carbosynth Limited 10mg/USD60()
Cayman Chemical Company USA
Clearsynth Labs Limited 25mg/USD500() India
Matrix Scientific 250mg/USD1890() USA
MedChemexpress Co., Ltd. 100mg/USD144();500mg/USD600() USA
MedKoo Biosciences, Inc. USA
ProbeChem
Santa Cruz Biotechnology, Inc. 25mg/USD150() USA
Shanghai Haoyuan Chemexpress Co., Ltd. 100mg/USD144();500mg/USD600() China
Target Molecule Corp. 10mg/USD23();25mg/USD46();50mg/USD75();100mg/USD135() USA
10

Related Products

Other Forms of 169590-41-4

Name CAS No Formula MW

Recommended Compounds in COX

Name CAS No Formula MW
Isoorientin 4261-42-1 C21H20O11 448.3769
Maslinic acid 4373-41-5 C30H48O4 472.7
Aceclofenac 89796-99-6 C16H13Cl2NO4 354.18
Zaltoprofen 74711-43-6 C17H14O3S 298.36
Ketorolac 74103-06-3 C15H13NO3 255.27
Loxoprofen 68767-14-6 C15H18O3 246.3
Mefenamic acid 61-68-7 C15H15NO2 241.29
Nabumetone 42924-53-8 C15H16O2 228.29
Triflusal 322-79-2 C10H7F3O4 248.16
Diclofenac (diethylamine) 78213-16-8 C18H22Cl2N2O2 369.29
Bufexamac 2438-72-4 C12H17NO3 223.27
Acemetacin 53164-05-9 C21H18ClNO6 415.82
Phenacetin 62-44-2 C10H13NO2 179.22
Tenoxicam 59804-37-4 C13H11N3O4S2 337.37
Flunixin (meglumine) 42461-84-7 0.0
Lornoxicam 70374-39-9 C13H10ClN3O4S2 371.82
Nimesulide 51803-78-2 C13H12N2O5S 308.31
Tolfenamic Acid 13710-19-5 C14H12ClNO2 261.7
Fenoprofen (Calcium) 34597-40-5 C30H26CaO6 522.6
Meloxicam 71125-38-7 C14H13N3O4S2 351.4

Recommended Compounds in Same Indication

Name CAS No Formula MW
11

Route of Synthesis

12

References

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More Information

Deracoxib

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