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26095-59-0 (Otilonium (bromide))

1

Identification

Otilonium (bromide) Otilonium (bromide)
Name Otilonium (bromide)
Formula C29H43BrN2O4
MW 563.57
CAS No. 26095-59-0
EINECS 247-457-4
Smiles O=C(OCC[N+](CC)(CC)C)C1=CC=C(NC(C2=CC=CC=C2OCCCCCCCC)=O)C=C1.[Br-]
Synonyms Doralin;Octylonium bromide;SP63;Spasmomen; N,N-diethyl-N-methyl-2-((4-(2-(octyloxy)benzamido)benzoyl)oxy)ethanaminium bromide
InChI InChI=1S/C29H42N2O4.BrH/c1-5-8-9-10-11-14-22-34-27-16-13-12-15-26(27)28(32)30-25-19-17-24(18-20-25)29(33)35-23-21-31(4,6-2)7-3;/h12-13,15-20H,5-11,14,21-23H2,1-4H3;1H
2

Introduction

Otilonium Bromide is an antimuscarinic used as a spasmolytic agent. Target: mAChR Otilonium bromide inhibited the generation of ACh-induced calcium signals in a dose dependent manner (IC50=880 nM) [1].

Background Information

Otilonium Bromide is an antimuscarinic used as a spasmolytic agent. ......by BOC Sciences
Otilonium bromide is an antimuscarinic. ......by Selleck Chemicals LLC
Otilonium bromide is an antimuscarinic. ......by Target Molecule Corp.
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Protocol(Only for Reference)

Cell Experiment

Animal Experiment

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Physical and Chemical Properties

Appearance:White to off-white Solid EBNumber:EB000012072

Storage condition

Solubility

DMSO 110 mg/mL; Water 110 mg/mL by MedChemexpress Co., Ltd.
(25°C) * In vitro DMSO 113 mg/mL (200.5 mM); Water113 mg/mL (200.5 mM); Ethanol113 mg/mL (200.5 mM) by Selleck Chemicals LLC
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Mechanism and Indication

Signaling Pathways Neuronal Signaling GPCR/G Protein
Target mAChR
Research Area Neurological Disease
Indications
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Clinical Information

Product Name Sponsor & Collaborators Indications Start Date End Date Phase
Otilonium (bromide) - Launched
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Safety Data of Otilonium (bromide)

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Spectral Information

9

Suppliers List

Company Price and Availability Country/Region
AA Blocks LLC
Apexbio Technology LLC USA
BOC Sciences
Beijing Dezhong Wanquan Medicines Technological Development Co., Ltd. China
Beijing Mediking Biopharm Co., Ltd. China
Biochempartner Co., Ltd China
CHEMSCENE, LLC 10mg/USD72();50mg/USD108() USA
Huzhou Hengyuan Biochem. Tech. Co., Ltd. China
MedChemexpress Co., Ltd. 10mg/USD72();50mg/USD108() USA
Selleck Chemicals LLC 10mg/USD97(In stock);10mM/1mLIn DMSO/USD130(In stock) USA
Shanghai Haoyuan Chemexpress Co., Ltd. 10mg/USD72();50mg/USD108() China
Suzhou Howsine Biological Technology Co., Ltd. China
Target Molecule Corp. 2mg/USD36();10mg/USD98();50mg/USD167();100mg/USD283() USA
Zhejiang Esun Chemical Co., Ltd. China
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Related Products

Other Forms of 26095-59-0

Name CAS No Formula MW
Otilonium 105360-89-2 C29H43N2O4+ 483.66

Recommended Compounds in mAChR

Name CAS No Formula MW
Pilocarpine (Hydrochloride) 54-71-7 C11H17ClN2O2 244.72
Imidafenacin 170105-16-5 C20H21N3O 319.4
Flavoxate (hydrochloride) 3717-88-2 C24H26ClNO4 427.92
Homatropine (Bromide) 51-56-9 C16H22BrNO3 356.25
Benztropine (mesylate) 132-17-2 C22H29NO4S 403.54
Arecoline (hydrobromide) 300-08-3 C8H14BrNO2 236.11
Trospium (chloride) 10405-02-4 C25H30ClNO3 427.96
Tiotropium (bromide hydrate) 139404-48-1 C19H24BrNO5S2 490.43
Revefenacin 864750-70-9 C35H43N5O4 597.747
Oxybutynin (chloride) 1508-65-2 C22H32ClNO3 393.95
Gallamine Triethiodide 65-29-2 C30H60I3N3O3 891.53
Bethanechol (chloride) 590-63-6 C7H17ClN2O2 196.68
Atropine (sulfate monohydrate) 5908-99-6 C34H50N2O11S 694.83
Methscopolamine (bromide) 155-41-9 C18H24BrNO4 398.29
Irsogladine (maleate) 84504-69-8 C13H11Cl2N5O4 372.16
Irsogladine 57381-26-7 C9H7Cl2N5 256.09
Tropicamide 1508-75-4 C17H20N2O2 284.35
Oxybutynin 5633-20-5 C22H31NO3 357.49
Ipratropium (bromide) 22254-24-6 C20H30BrNO3 412.36
Scopolamine (hydrobromide) 114-49-8 C17H22BrNO4 384.26

Recommended Compounds in Same Indication

Name CAS No Formula MW
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Route of Synthesis

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References

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More Information

Otilonium (bromide)

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