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Suzhou Howsine Biological Technology Co., Ltd.

44

Basic Information

Company Name:Suzhou Howsine Biological Technology Co., Ltd.

Business Type:Chemical manufacturer since 2007

Total NO.Employees:

Country/Region:China

Certificates:

Year Established:

Introduction of Suzhou Howsine Biological Technology Co., Ltd.

Web: www.howsine.com TEL:+86 (512) 6812-8052 Fax:+86 (512) 6812-8051 Email:[email protected],[email protected]

Products of Suzhou Howsine Biological Technology Co., Ltd.

  • Chemical Name: Synephrine (hydrochloride)
    CAS No.: 5985-28-4 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Oxedrine hydrochloride; 4-(... Quality Control & MSDS Files:
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    Brief introduction:

    Synephrine Hcl(Oxedrine) is an alkaloid; synephrine produces most of its biological effects by acting as an agonist at adrenergic receptors. IC50 value: Target: adrenergic receptor agonist There is some evidence that synephrine also has weak activity at 5-HT receptors, and that it interacts with TAAR1 (trace adrenergic amine recepto...

  • Chemical Name: Latanoprost
    CAS No.: 130209-82-4 Purity: Appearances: Colorless to light yellow Oil
    Brand: Synonyms: Propan-2-yl 7-[3,5-dihydrox... Quality Control & MSDS Files:
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    Brief introduction:

    Latanoprost is a prostaglandin F2a analogue used for controlling the progression of glaucoma or ocular hypertension. Target: Others Latanoprost is an ester prodrug analogue of prostaglandin F2 alpha which effectively reduces intraocular pressure (IOP) by increasing uveoscleral outflow rather than altering conventional trabeculo-canal...

  • Chemical Name: Biotin
    CAS No.: 58-85-5 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Vitamin H; Vitamin B7; Hexa... Quality Control & MSDS Files:
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    Brief introduction:

    Biotin is a water-soluble, enzyme co-factor present in minute amounts in every living cell. Target: Others Biotin is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.

  • Chemical Name: Otilonium (bromide)
    CAS No.: 26095-59-0 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Doralin;Octylonium bromide;... Quality Control & MSDS Files:
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    Otilonium Bromide is an antimuscarinic used as a spasmolytic agent. Target: mAChR Otilonium bromide inhibited the generation of ACh-induced calcium signals in a dose dependent manner (IC50=880 nM) [1].

  • Chemical Name: Olopatadine (hydrochloride)
    CAS No.: 140462-76-6 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: (Z)-11-[3-(Dimethylamino)pr... Quality Control & MSDS Files:
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    Olopatadine HCl is a histamine blocker used to treat allergic conjunctivitis. Target: Histamine Receptor Olopatadine is one of the second-generation histamine H1 receptor antagonists that are treated for allergic disorders.

  • Chemical Name: Guanidine (hydrochloride)
    CAS No.: 50-01-1 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: guanidine hydrochloride Quality Control & MSDS Files:
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    Brief introduction:

    Guanidine HCl, the crystalline compound of strong alkalinity formed by the oxidation of guanine, is a normal product of protein metabolism and a protein denaturant. Target: Others Guanidine HCl is the most popular protein denaturant.

  • Chemical Name: Natamycin
    CAS No.: 7681-93-8 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Natamycin; (1R,3S,5R,7R,8E,... Quality Control & MSDS Files:
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    Brief introduction:

    Natamycin (pimaricin) is an antifungal macrolide polyene that binds to cell membrane sterols. Target: Antifungal Natamycin (INN), also known as pimaricin and sometimes sold as Natacyn, is a naturally occurring antifungal agent produced during fermentation by the bacterium Streptomyces natalensis, commonly found in soil.

  • Chemical Name: Benzaldehyde, α-chloro-
    CAS No.: 98-88-4 Purity: Appearances:
    Brand: Synonyms: alpha-Chlorobenzaldehyde; B... Quality Control & MSDS Files:
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    Brief introduction:

    A colorless fuming liquid with a pungent odor. Flash point 162°F. Lachrymator, irritating to skin and eyes. Corrosive to metals and tissue. Density 10.2 lb / gal. Used in medicine and in the manufacture of other chemicals.

  • Chemical Name: Indole-3-carbinol
    CAS No.: 700-06-1 Purity: Appearances:
    Brand: Synonyms: 3-Hydroxymethylindole; 3-In... Quality Control & MSDS Files:
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    Brief introduction:

    Indole-3-carbinol suppresses <b>NF-κB</b> activity and also is an <b>Aryl hydrocarbon receptor</b> (<b>AhR</b>) agonist.

  • Chemical Name: 2-Chloro-3-hydroxypyridine
    CAS No.: 6636-78-8 Purity: Appearances:
    Brand: Synonyms: 2-Chloro-3-pyridinol; 2-chl... Quality Control & MSDS Files:
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  • Chemical Name: Roflumilast
    CAS No.: 162401-32-3 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: 3-(Cyclopropylmethoxy)-N-(3... Quality Control & MSDS Files:
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    Brief introduction:

    Roflumilast(Daliresp) is a drug which acts as a selective, long-acting inhibitor of the enzyme PDE-4 with an IC50 of 0.8 nM.

  • Chemical Name: Tofacitinib (citrate)
    CAS No.: 540737-29-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Tasocitinib citrate;CP-6905... Quality Control & MSDS Files:
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    Brief introduction:

    Tofacitinib citrate (CP-690550 citrate) is a novel inhibitor of JAK3 with IC50 of 1 nM, 20- to 100-fold less potent against JAK2 and JAK1. IC50 value: 1 nM [1] Target: JAK3 in vitro: CP-690550 is a specific, orally inhibitor of JAK3, it is 20- to 100-fold less potent for JAK2 and JAK1 with IC50 of 20 nM and 112 nM, respectively.

  • Chemical Name: Azelnidipine
    CAS No.: 123524-52-7 Purity: Appearances: White to off-white solid
    Brand: Synonyms: 2-Amino-1,4-dihydro-6-methy... Quality Control & MSDS Files:
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    Brief introduction:

    Azelnidipine(CS 905; Calblock) is a novel dihydropyridine derivative, a L-type calcium channel blocker, and an antihypertensive. IC50 value: Target: L-type calcium channel Acute administration of azelnidipine prevents a sudden drop of cardiac function after acute stress.

  • Chemical Name: Alogliptin (Benzoate)
    CAS No.: 850649-62-6 Purity: Appearances: White to off-white solid
    Brand: Synonyms: Nesina; SYR 322; (R)-2-((6-... Quality Control & MSDS Files:
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    Brief introduction:

    Alogliptin benzoate(SYR 322) is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. IC50 value: <10 nM Target: DPP4 Alogliptin is an orally administered, anti-diabetic drug in the DPP-4 inhibitor class.

  • Chemical Name: CX-4945
    CAS No.: 1009820-21-6 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: Silmitasertib;CX 4945;CX494... Quality Control & MSDS Files:
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    Brief introduction:

    CX-4945 (Silmitasertib) is a potent and selective ATP-competitive small molecule protein kinase CK2 inhibitor with a Ki and an IC50 of 0.38 and 1 nM for recombinant human CK2α, respectively.

  • Chemical Name: Rivaroxaban
    CAS No.: 366789-02-8 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Xarelto; BAY 59-7939; (S)-5... Quality Control & MSDS Files:
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    Brief introduction:

    Rivaroxaban (Xarelto; BAY 59-7939) is a novel, oral, direct Factor Xa (FXa) inhibitor in late-stage development for the prevention and treatment of thromboembolic disorders. IC50 value: Target: Factor Xa Rivaroxaban (Xarelto; BAY 59-7939) inhibits clot-associated,free FXa activity,and prothrombinase activity, in addition, it reduces...

  • Chemical Name: Dabigatran etexilate
    CAS No.: 211915-06-9 Purity: Appearances: White to off-white Solid
    Brand: Synonyms: Prazaxa; BIBR 1048; BIBR-10... Quality Control & MSDS Files:
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    Brief introduction:

    Dabigatran etexilate(BIBR-1048) is the orally active prodrug of dabigatran; Dabigatran is a reversible and selective, direct thrombin inhibitor (DTI) with Ki value of 4.5 nM. IC50 Value: 4.5 nM (Ki); 10 nM(Thrombin-induced platelet aggregation) [1] in vitro: Dabigatran selectively and reversibly inhibited human thrombin(Ki: 4.5 nM) a...

  • Chemical Name: Entinostat
    CAS No.: 209783-80-2 Purity: Appearances: Light yellow to yellow Solid
    Brand: Synonyms: MS-275; SNDX-275; MS 275; S... Quality Control & MSDS Files:
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    Brief introduction:

    Entinostat (MS-275; SNDX 275) strongly inhibits HDAC1 and HDAC3 with IC50 of 0.51 μM and 1.7 μM. IC50 Value: 0.51 μM(HDAC1); 1.7 μM(HDAC3) Target: HDAC1/3 in vitro: MS-275 shows inhibitory to HDACs by 2'-amino group.

  • Chemical Name: Dacomitinib
    CAS No.: 1110813-31-4 Purity: Appearances: White to off-white solid
    Brand: Synonyms: PF-00299804; PF-299804; PF ... Quality Control & MSDS Files:
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    Brief introduction:

    Dacomitinib(PF299804; PF-00299804) is a potent, orally available, irreversible tyrosine kinase HER 1 (EGFR), HER2 and HER4 inhibitor with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2 and ERBB4, respectively.

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